dugesia/neurodegenerative diseases

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Photonegative response in brown planaria (Dugesia tigrina) following regeneration.

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The photonegative response was investigated in regenerated brown planaria (Dugesia tigrina). Old, middle, and young animals were tested, bisected into heads and tails, and allowed to regenerate. Different regeneration times affected function, with generally older planaria achieving full

Regeneration in an evolutionarily primitive brain--the planarian Dugesia japonica model.

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A unique aspect of planarians is that they can regenerate a brain from somatic pluripotent stem cells called neoblasts, which have the ability to produce themselves (self-renew) and to give rise to all missing cell types during regeneration. Recent molecular studies have revealed that the planarian

Expression and functional analysis of flotillins in Dugesia japonica.

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FLOTILLIN-1 and FLOTILLIN-2 are membrane rafts associated proteins that have been implicated in insulin and growth factor signaling, endocytosis, cell migration, proliferation, differentiation, cytoskeleton remodeling and membrane trafficking. Furthermore, FLOTILLINs also play important roles in the

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