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dyspepsia/inflammation
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Treatment of non-inflammatory and non-infectious bowel disorders
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TECHNICAL FIELD
This invention relates to the production and use of therapeutic agents for the treatment of certain bowel disorders, namely disorders arising from unknown or non-obvious causes, which are unaccompanied by inflammation and are not due to detectable infection by known pathogenic
Compounds as delta opioid agonists
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This application claims priority from U.K. application serial no. 9804734.3 which was filed on Mar. 5, 1998.
The present invention relates to compounds, including inter alia pharmaceutical compositions comprising the same and methods for making the same.
In particular, the present invention relates
Salts of trimebutine and N-desmethyl trimebutine
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FIELD OF INVENTION
The present invention relates to unique salts of trimebutine and N-monodesmethyl trimebutine, and their corresponding stereoisomers, having improved analgesic properties useful in the treatment of visceral pain in general and more particularly in the treatment of conditions
Synthetic lactone formulations and methods of use
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FIELD OF THE INVENTION
The present inventions are generally in the fields of pharmaceutically active lactones, their pharmaceutical formulations, and method of use thereof, and methods for the synthetic preparation of chemically functionalized lactones useful therefor as anticancer, antiinfective
Synthetic lactone formulations and method of use
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The present inventions are generally in the fields of pharmaceutically active lactones, their pharmaceutical formulations, and method of use thereof, and methods for the synthetic preparation of chemically functionalized lactones useful therefor as anticancer, antiinfective and anti-inflammatory
GABA analogs to prevent and treat gastrointestinal damage
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FIELD OF THE INVENTION
This invention relates to a method for preventing visceral and gastrointestinal damage such as gastric ulcers by administering a gamma-aminobutyric acid (GABA) analog, and for treating gastrointestinal diseases such as inflammatory bowel disorders (IBD), functional bowel
Methods of preventing and reducing the severity of stress-associated conditions
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates generally to the sympathetic nervous system and various stress-associated conditions and, in particular, to the .alpha.-2 adrenergic agonist, brimonidine.
2. Background Information
Conditions that are associated with or
Medicine for the treatment of illnesses of the respiratory organs
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TECHNICAL FIELD
The present invention relates to the use of gallic acids chenodeoxycholic acid and ursodeoxycholic acid or a combination thereof for the manufacture of a medicine.
The chemical designation of chenodeoxycholic acid is 3.alpha.,7.alpha.-Dihydroxy-5.beta.-cholan-24-oic-acid. The
Diagnosis and treatment of a disorder of the gastrointestinal tract
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BACKGROUND OF THE INVENTION
This invention relates to the therapy of irritable bowel syndrome (IBS), in particular, upper irritable bowel syndrome (non-ulcerative dyspepsia), and related conditions as hereinafter described.
Irritable bowel syndrome is the most common reason for referral to
Diagnosis and treatment of a disorder of the gastrointestinal tract
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BACKGROUND OF THE INVENTION
This invention relates to the therapy of irritable bowel syndrome (IBS), in particular, upper irritable bowel syndrome (non-ulcerative dyspepsia), and related conditions as hereinafter described.
Irritable bowel syndrome is the most common reason for referral to
Macrocyclic antagonists of the motilin receptor for treatment of gastrointestinal dysmotility disorders
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FIELD OF THE INVENTION
The present invention relates to novel conformationally-defined macrocyclic compounds that bind to and/or are functional modulators of the motilin receptor including subtypes, isoforms and/or variants thereof. These macrocyclic compounds possess appropriate pharmacological
Treatments for gastrointestinal disorders
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SEQUENCE LISTING
This application incorporates by reference in its entirety the Sequence Listing entitled "IW112PCT1US1a_ST25", containing 4.52 KB of data and last modified on May 11, 2016, in computer readable-format (CRF) and electronic .txt format, filed electronically herewith.
FIELD OF THE
Treatments for gastrointestinal disorders
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FIELD OF THE INVENTION
This invention relates to peptides, compositions and methods for treating gastrointestinal disorders.
SEQUENCE LISTING
This application incorporates by reference in its entirety the Sequence Listing entitled "IW087_seq_ST25.txt" (527 bytes), which was created Feb. 17, 2011 and
Methods and compositions for the treatment of gastrointestinal disorders
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SEQUENCE LISTING
This application incorporates by reference in its entirety the Sequence Listing entitled "Sequence Listing 22003040.txt", containing 33 kilobytes of data, created Aug. 13, 2008, and filed with the parent application U.S. application Ser. No. 11/930,696 on Aug. 18, 2008 in computer
Methods and compositions for the treatment of gastrointestinal disorders
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TECHNICAL FIELD
This invention relates to methods and compositions for treating various disorders, including gastrointestinal disorders, obesity, congestive heart failure and benign prostatic hyperplasia.
BACKGROUND
Irritable bowel syndrome (IBS) is a common chronic disorder of the intestine that
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