dyspepsia/neoplasms

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The optimal age threshold for screening upper endoscopy for uninvestigated dyspepsia in Taiwan, an area with a higher prevalence of gastric cancer in young adults.

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BACKGROUND It is estimated that 1% to 2% of patients with dyspepsia are associated with gastric cancer. To avoid missing gastric cancer, most guidelines recommend that patients over 45 years old should undergo EGD for uninvestigated dyspepsia. In Taiwan, however, the prevalence of gastric cancer in

Missing gastric cancer in dyspepsia.

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BACKGROUND Dyspepsia is common in gastric cancer, but also in many benign conditions. European Helicobacter pylori Study Group and American Gastroenterological Association guidelines recommend endoscopy in dyspepsia for patients with alarm symptoms or at age >45 years. However, recommendations are

Serum selenium level in patients with gastric non-cardia cancer and functional dyspepsia.

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BACKGROUND Gastric cancer (GC) is the most common gastrointestinal cancer in Iran. Helicobacter pylori (H. pylori) accounts as one of the main risk factors for gastric non-cardia cancer (GNCC). It is suggested that high serum selenium level may have a protective role in GNCC. In this cross-sectional

A double-blind, crossover study of controlled-release metoclopramide and placebo for the chronic nausea and dyspepsia of advanced cancer.

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To compare a novel controlled-release formulation of metoclopramide with placebo in patients with cancer-associated dyspepsia syndrome, 26 adult patients with a >/=1 month history of cancer-associated dyspepsia syndrome were randomized to receive either controlled-release metoclopramide 40 mg every

Draft genome sequences of Helicobacter pylori isolates from Malaysia, cultured from patients with functional dyspepsia and gastric cancer.

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Helicobacter pylori is the main bacterial causative agent of gastroduodenal disorders and a risk factor for gastric adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. The draft genomes of 10 closely related H. pylori isolates from the multiracial Malaysian population will provide

Comparative classification and grading of Helicobacter pylori gastritis in patients with gastric cancer and patients with functional dyspepsia.

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BACKGROUND It has previously been shown that corpus-dominant grade and activity of Helicobacter pylori gastritis in combination with intestinal metaplasia in the antrum or corpus are risk markers for the development of stomach cancer. If one point is scored for each of these three parameters, a

Is administration of proton pump inhibitors in functional dyspepsia worth the risk of developing gastric cancer: a Markov model to bridge the gap between scientific evidence and clinical practice.

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To formulate a decision analysis model based on recently published data that addresses the dilemma, whether improvement in quality of life rationalises continued proton pump inhibitors (PPI) use despite the risk of gastric cancer (GC) in patients with functional dyspepsia

Anti CagA antibody among patients with non-cardia gastric cancer in comparison with non-ulcer dyspepsia in an area with high incidence of gastric cancer.

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OBJECTIVE To evaluate the correlation between anti CagA antibody (Ab) and presence of gastric cancer. METHODS In a descriptive cross-sectional study during October 2003 to October 2005, in the Gastrointestinal Subspeciality Center in Razi Hospital, Rasht, Iran, we assessed anti-Helicobacter Ab

Clinical presentations of gastric small gastrointestinal stromal tumors mimics functional dyspepsia symptoms.

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OBJECTIVE To explore whether clinical presentations of gastric small gastrointestinal tumors (GISTs) mimics gastrointestinal dyspepsia symptoms. METHODS The endosonographic data of 167 patients who underwent endoscopic submucosal dissection at the Tianjin Medical University General Hospital, China

The corpus-predominant gastritis index can be an early and reversible marker to identify the gastric cancer risk of Helicobacter pylori-infected nonulcer dyspepsia.

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BACKGROUND Corpus-predominant gastritis index (CGI) is an early histological marker to identify Helicobacter pylori-infected gastric cancer relatives at risk of cancer. This study validated whether CGI is more prevalent in H. pylori-infected nonulcer dyspepsia (NUD) subjects than in duodenal ulcer

Upper digestive tract dyspepsia and early gastric cancer.

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OBJECTIVE The study of the frequency and evolution of upper digestive tract dyspepsia in a group of patients operated for early gastric cancer (EGC) and to perform a strategy of diagnosis for the patients with long term upper digestive tract dyspepsia. METHODS Clinical data of 35 patients operated

Association between interleukin-1β and tumor necrosis factor-α polymorphisms and symptoms of dyspepsia.

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Interleukin (IL)‑1β, and tumor necrosis factor (TNF)‑α have significant roles in the mediation of inflammatory immune responses and are also potent inhibitors of gastric acid secretion in the stomach. The present study aimed to investigate the associations between polymorphisms at position ‑31 (T>C)

Choice of age cut-off for endoscopy in dyspepsia in developing countries according to incidence of gastric cancer.

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Endoscopic examination of all patients with dyspepsia is hard to perform, because of high annual prevalence of dyspepsia and limited resource availability, especially in developing countries. Aim was to establish age cut off for upper endoscopy in dyspeptic patients without alarming features

Does endoscopy diagnose early gastrointestinal cancer in patients with uncomplicated dyspepsia?

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BACKGROUND Recent guidelines from NICE have proposed that open access gastroscopy is largely limited to patients with "alarm" symptoms. OBJECTIVE This study reviewed the outcome of all our patients with verified oesophageal or gastric carcinoma who presented with uncomplicated dyspepsia to see if

[Optimal age for gastric cancer screening in patients with dyspepsia without alarm symptoms].

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OBJECTIVE To determine the optimal age for screening endoscopy on patients with dyspepsia without alarm symptoms to avoid missing gastric cancer. METHODS A Cross sectional study was performed (2001-2005). 285 cases of patients with dyspepsia and gastric cancer were found at Arzobispo Loayza National

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