elastase/obesity

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Pediatric Longitudinal Cohort Study of Chronic Pancreatitis

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Disease Burden Pain. The pattern of the pain (constant versus episodic), its frequency, duration, visits to the emergency room or hospitalizations for pain, impact of pain on quality of life will be recorded in questionnaires. The intensity of the pain will be measured at enrollment, during an

EnVision CF Multicenter Study of Glucose Tolerance in Cystic Fibrosis

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A. Hypotheses and Specific Aims: Cystic Fibrosis Related Diabetes Mellitus (CFRD) has been identified by the CF community as one of the top ten priorities for CF research1. In CF, clinical decline due to dysglycemia begins early, prior to the diagnosis of CFRD2 and increases pulmonary decline and

Anti-Inflammatory Small Drug Adjunctive Therapy for Type 2 Diabetes

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Type 2 diabetes (T2D) is characterized by concomitant insulin resistance and pancreatic beta cell dysfunction. Disease prevalence continues to increase around the globe and is currently estimated to be at more than 385 million affected people. As many as 1 in 3 people in the United States could have

Defining the Molecular and Physiological Mechanisms of Pancreatic Islet Cell Dysfunction Which Lead to Type 2 Diabetes

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Introduction: Working with collaborators as part of ongoing genetic studies, the investigators have identified several genetic variations (DNA changes) associated with the production of and processing of insulin and are trying to understand how these genetic variations cause differences in people's

The Diagnosis of Chronic Pancreatitis

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WP 1: Exocrine function testing Aims: Evaluating an endoscopic short test in patients with suspected pancreatic disease. Main focus on Chronic pancreatitis. (Collaborations to other patient groups in other protocols and to a group of healthy controls. ) Methods: Secretintsimulated Endoscopic short

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