entandrophragma/ulcer

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Spasmolytic activity of methyl angolensate: a triterpenoid isolated from Entandrophragma angolense.

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Entandrophragma angolense is a medicinal plant used in folk medicine against several diseases including peptic ulcer. Methyl angolensate was isolated from E. angolense by recrystallization from methanol. The needle-like crystals were characterized and tested on isolated rabbit jejunum, guinea pig

Gastroprotective effects of an aqueous extract of Entandrophragma utile bark in experimental ethanol-induced peptic ulceration in mice and rats.

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An aqueous extract of Entandrophragma utile bark was shown to be efficacious in preventing experimental ethanol-induced ulcers in rats. A therapeutic dose equivalent to 50 g/kg of bark orally caused total protection without lethality in the animals employed. The formation of a protective pellicle

Effect of the aqueous extract of entandrophragma utile bark on gastric acid secretion in ghosh and schild rat preparations.

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OBJECTIVE The reduction of aggressive factors such as gastric acid is considered a key target of gastrointestinal protection. We investigated the antisecretory effect of the aqueous bark extract of E. utile, a Nigerian traditional medicinal preparation used for ulcers. METHODS Male rats were

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