Participants were randomly divided based on age, sex and severity of TBI in two groups. Randomization lists was computer-generated by a statistician and participants, project managers and employees at the clinic are completely unaware (blind) about intervention and control groups. At the first visit, baseline data were gathered and patients received EGCG supplement was in the form of 400 mg oral capsules with a purity of 80% catechin. EGCG powder of each capsule was dissolved in 10 ml deionized water and given to patients via gavage (1 capsule per day) for a week.

Placebo group only received 10 ml of deionized water via gavage for a week.

Traumatic Brain Injury

EGCG

Placebo (deionized water)

NNFTRI clinic

Effect of Epigallocatechin -3-gallate Supplementation in Traumatic Brain Injury Patients

Effect of Green Tea Epigallocatechin -3-gallate Supplementation on Traumatic Brain Injury Patients' Outcomes

Duration of mechanical ventilation is recorded by a nurse who is blinded to grouping and reported in days.

Dr Azita Hekmatdoost

Associate professor

National Nutrition and Food Technology Institute

Tehran University of Medical Sciences

40 subjects will receive 800 mg EGCG orally per day for 6 months versus 40 subjects will receive Brown Rice pill for 6 months

40 subjects will receive 800 mg brown rice pills orally per day for 6 months versus 40 subjects will receive EGCG capsule for 6 months

Leiomyoma

A randomized double-blind placebo-controlled clinical trial will be conducted with 80 women of reproductive age,the 80 women will be allocated into two groups, 40 each. Each group will be given one of two interventions: The first is 2 capsules of (EGCG which is green tea extract, taken orally with food on daily basis for 6 months, each capsule contain 326.25 mg decaffeinated EGCG,The second group will receive matched (color, taste and texture) placebo for a period of 6 months.

EGCG ( Green Tea extract)

40 subjects will receive 800 mg EGCG orally daily for 6 months, the other 40 subject will receive brown rice pills for the same duration.

epigallocatechin/hemorrhage

Effect of Epigallocatechin -3-gallate Supplementation in Traumatic Brain Injury Patients

Green Tea Extract: a Non-Surgical Alternative for Treatment of Uterine Fibroids

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