epinephrine/atrophy

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Nerve terminal degeneration in the rat iris observed following chronic topical 2% epinephrine and 0.1% dipivalyl epinephrine: a quantitative comparison of electron microscopic observations and tissue norepinephrine levels.

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This is the first report of nerve terminal degeneration within the iris following topical dipivalyl epinephrine 0.1% treatment. A quantitative comparison of the effects of topically applied epinephrine 2%, dipivalyl epinephrine 0.1%, and placebo vehicle on the nerve terminals within the iris of a

Post-ganglionic chemical sympathectomy of the cat nictitating membrane following systemic epinephrine: degeneration of nerve terminals followed by regeneration.

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The present study was designed to provide further evidence that high doses of systemically administered epinephrine can result in a post-ganglionic chemical sympathectomy and to look for evidence of regeneration of nerve terminals. Three days following the systemic administration of a high dose of

Epinephrine Deteriorates Pulmonary Gas Exchange in a Rat Model of Bupivacaine-Induced Cardiotoxicity: A Threshold Dose of Epinephrine.

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OBJECTIVE The study goal was to compare the effect of epinephrine in different doses on pulmonary gas exchange in a rat model of bupivacaine-induced cardiac depression. METHODS Twenty-four adult male Sprague-Dawley rats were divided into 4 groups (n = 6), and each group received a bupivacaine

Stability of the intra-epithelial component of the blood-testis barrier in epinephrine-induced testicular degeneration in Syrian hamsters.

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Adult male Syrian hamsters were given daily intraperitoneal injections of epinephrine (1.0 mg/kg) and papaverine, a vasodilator, (60 mg/kg) for a period of ten days. After the treatment period, lanthanum and horseradish peroxidase tracer studies were used to examine the intra-epithelial component of

Immunohistochemical quantitative study of the peritubular lamina propria after induction of testicular atrophy induced by epinephrine.

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Changes in the testicular peritubular lamina propria in rats treated for 1-11 weeks with intra-scrotal injections of epinephrine were studied by quantitative immunohistochemical methods. In control testes, BrdU-labelled nuclei (proliferating cells) were observed only in spermatogonia and some

Evidence for retrograde degeneration of epinephrine neurons in Alzheimer's disease.

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Alzheimer's disease (AD) is associated with a progressive loss of locus ceruleus neurons. These noradrenergic neurons receive a major afferent projection from epinephrine neurons in epinephrine cell groups in the brainstem. The epinephrine neurons have a specific enzymatic marker, phenylethanolamine

Myoid cell proliferation in rat seminiferous tubules after ischaemic testicular atrophy induced by epinephrine. Morphometric and immunohistochemical (bromo-deoxyuridine and PCNA) studies.

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The proliferation of peritubular myoid cells in the testes of rats treated for 1-11 weeks with intra-scrotal injections of epinephrine was investigated using immunohistochemistry and quantitative histology. The percentage of peritubular cells that were immunopositive for proliferating cell nuclear

Epinephrine at doses used in dentistry deteriorates platelet retention rate.

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Epinephrine promotes platelet aggregation through alpha 2 receptor-mediated mechanisms. In this study, the change in the platelet retention rate (PRR) was investigated before and after submucosal epinephrine injection with or without lidocaine in oral surgical patients during isoflurane-nitrous

Epinephrine induces rapid deterioration in pulmonary oxygen exchange in intact, anesthetized rats: a flow and pulmonary capillary pressure-dependent phenomenon.

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BACKGROUND Previous studies indicate epinephrine adversely affects arterial oxygenation when administered in a rat model of local anesthetic overdose. The authors tested whether epinephrine alone exerts similar effects in the intact animal. METHODS Anesthetized rats received a single intravenous

Degeneration of nerve terminals in cats following systemic epinephrine: depletion of tissue norepinephrine correlated with ultrastructural changes.

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An electron microscopic study of degeneration of nerve terminals after administration of epinephrine.

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Testicular atrophy in rats following epinephrine administration.

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Testicular atrophy in rats following epinephrine administration.

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Ptosis in the rat following topically administered 2% epinephrine.

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Commercially available 2% epinephrine instilled twice daily in one eye of 15 rats resulted in ptosis after 4 weeks treatment. The ptosis was indistinguishable from that observed following topical treatment with 6-hydroxydopamine 20% and surgical sympathectomy. Ptosis in both epinephrine- and

Effects of graded doses of epinephrine during asphxia-induced bradycardia in newborn lambs.

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To study the hemodynamic effects of graded doses of epinephrine (EPI) in a newborn animal model of hemodynamically significant bradycardia, we performed the following study. Ten newborn lambs were chronically instrumented with catheters and flow transducers so that systemic, pulmonary arterial, left

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