erythema multiforme/seizures

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Drug-induced erythema multiforme: a possible immunologic pathogenesis.

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A 37-year-old female developed erythema multiforme 17 days after beginning carbamazepine for complex partial seizures. The carbamazepine was discontinued and phenytoin begun. A new rash developed and phenytoin therapy was stopped. In vitro immunologic studies were conducted in an effort to

Erythema multiforme associated with prophylactic use of phenytoin during cranial radiation therapy.

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OBJECTIVE A case of erythema multiforme associated with prophylactic use of phenytoin during cranial radiation therapy is reported. CONCLUSIONS A 60-year-old woman with intraductal adenocarcinoma of the breast and cerebral metastasis who had an implanted central venous catheter arrived at the

Erythema multiforme and Stevens-Johnson syndrome in patients receiving cranial irradiation and phenytoin.

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In 15 months we encountered eight patients with intracranial tumors who developed erythema multiforme (EM) or erythema multiforme bullosa (Stevens-Johnson syndrome). All occurred shortly after use of phenytoin (DPH) and brain radiation therapy (WBRT). The clinical picture differed from the classic

Methotrexate-induced erythema multiforme: a case report and review of the literature.

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BACKGROUND Mucosal affectation may be a direct cytotoxic or cytostatic effect of methotrexate. OBJECTIVE To highlight the diagnostic procedure and treatment intervention erythema multiforme complicating methotrexate-induced allergic stomatitis. METHODS The patient was a 60-year-old man suffering

Erythema multiforme associated with phenytoin and cranial radiation therapy: a report of three patients and review of the literature.

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BACKGROUND Intracranial malignancies (primary and metastatic) are often complicated by seizure activity. Phenytoin (Dilantin) is typically employed as prophylactic anticonvulsant in this setting. Uncommonly, erythema multiforme (EM) can develop in such patients at the port site during or soon after

Lamotrigine-induced erythema multiforme mimicking contact dermatitis.

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Erythema multiforme is an acute, hypersensitivity reaction of the skin often secondary to medications. Lamotrigine is a relatively new anticonvulsant medication approved for seizure and psychiatric disorders. Although the overall incidence of cutaneous reactions to lamotrigine is high, the incidence

Erythema multiforme, Stevens Johnson syndrome, and toxic epidermal necrolysis syndrome in patients undergoing radiation therapy: a literature review.

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OBJECTIVE Erythema multiforme (EM), Stevens Johnson syndrome (SJS), and toxic epidermal necrolysis syndrome (TENS) are exfoliative disorders that may present as complications in some patients undergoing radiotherapy. The purpose of this literature review was to determine the reported frequency of

Carbamazepine-induced eruption histologically mimicking mycosis fungoides.

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Carbamazepine is an important drug used in the management of seizures, trigeminal neuralgia, and chronic pain syndromes. It has been associated with a variety of adverse skin reactions including urticaria, lichenoid eruptions, erythroderma, erythema multiforme, Stevens-Johnson syndrome, and toxic

Multi-indication carbamazepine and the risk of severe cutaneous adverse drug reactions in Korean elderly patients: a Korean health insurance data-based study.

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OBJECTIVE To evaluate the risk of severe cutaneous adverse drug reactions (SCAR) after exposure to multi-indication antiepileptic drugs for in Korean elderly patients. METHODS We used a nationwide database from the Korean Health Insurance Review and Assessment Service claims constructed for the

EMPACT syndrome.

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Phenytoin is commonly used an antiepileptic medication for seizure prophylaxis in patients with brain metastases. In these oncology patients group, phenytoin-induced severe adverse reactions may occur. Antiepileptic, particularly phenytoin-induced severe skin reactions including Stevens-Johnson

Lamotrigine and severe skin eruptions.

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Lamotrigine is an important new addition to the drugs used to treat people with seizure disorders, but disconcerting are reports of a higher than expected incidence of severe skin reaction among children. Using automated data from three HMOs, we conducted a retrospective investigation of children

Patch testing in the detection of cutaneous reactions caused by carbamazepine.

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Carbamazepine is a widely used antiepileptic drug associated with various side effects including skin eruptions. Peroral provocation test with any suspected drug is a reliable method of investigating the etiology: however, it is both laborious and potentially dangerous to the patient. Patch testing

Myocarditis with complete atrioventricular block associated with herpes simplex virus infection: report of one case.

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Myocarditis with complete atrioventricular block is a very unusual complication of the herpex simplex infection. We report a 10-year-old boy infected very likely by the herpes simplex virus and who presented with high fever, erythema multiforme, complete atrioventricular block, and Adams-Stokes

[Lamotrigine induced hypersensitivity syndrome in children: a case report].

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Drug induced hypersensitivity syndrome (DIHS) is often manifested as severe systemic drug trans-reactions characterized by acute and extensive skin lesions (mostly measles-like rash), fever, enlargement of lymph nodes, multiple organ involvement (hepatitis, nephritis, and pneumonia), eosinophilia

Smallpox vaccination and adverse reactions. Guidance for clinicians.

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The guidance in this report is for evaluation and treatment of patients with complications from smallpox vaccination in the preoutbreak setting. Information is also included related to reporting adverse events and seeking specialized consultation and therapies for these events. The frequencies of

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