ferula/hemorrhage

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[Hemorrhagic diathesis from the juice of the roots of Ferula communis; behavior of the fibrinogen].

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[Hemorrhagic diathesis from juice of the roots of Ferula communis; behavior of the V factor of Owren].

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Ferula communis variety brevifolia intoxication of sheep.

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Sheep given powdered Ferula communis variety brevifolia at dosage of 2.5 g/kg of body weight/d for 15 days developed classical clinical signs of intoxication: anorexia, somnolence, apparent weakness, and hemorrhage. Marked reduction of vitamin K-dependent coagulation factors and prolongation of

[Anticoagulant activity of coumarins from Ferula communis L].

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Ferula communis is an ombelliferous plant of the Mediterranean regions. It is represented in Morocco by two varieties: brevifolia and genuina. The later is very rich in a soap or resinous gum. This product, collected from the roots, is largely used in traditional medicine. It is know as fessoukh in

Acute toxicity of ferulenol, a 4-hydroxycoumarin isolated from Ferula communis L.

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The acute LD50s of ferulenol were determined in albino mice by single po or ip as 2,100 and 319 mg/kg bw, respectively. Ferulenol had a higher LD50 compared to warfarin and thus has a lower acute toxicity. Three days after ferulenol administration, dosed animals showed hypoprothrombinemia with

Characterization of anti-coagulant properties of prenylated coumarin ferulenol.

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We investigated the mechanisms underlying severe bleeding occurring upon consumption of Ferula communis. The prenylated coumarin ferulenol extracted from this plant did not directly affect blood coagulation but showed hepatocyte cytotoxicity and, at non-cytotoxic concentrations (<100 nM), impaired

Pharmacological and Therapeutic Aspects of Plants from the Genus Ferula: a Comprehensive Review.

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Inspired by nature, humankind has been able to attain significant achievements in the drug and food industries. Particularly, medicinal plants are a rich source of medicinal, cosmetic, sanitary, and aromatic substances. Genus Ferula from Apiaceae family is a plant genus that possesses over 170

Examples of poisonous plants in Israel of importance to animals and man.

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Several plants causing poisoning in herbivores in Israel have an association with human health. Ferula communis (giant fennel) contains a potent anticoagulant and induces severe haemorrhagic diathesis in grazing ewes, or similar changes in utero in lambs. These and other teratogenic changes have

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