OBJECTIVE
Oral anticoagulation with vitamin K antagonists (VKAs) for stroke prevention in atrial fibrillation (AF) is effective but has significant limitations. AZD0837, a new oral anticoagulant, is a prodrug converted to a selective and reversible direct thrombin inhibitor (AR-H067637). We report
OBJECTIVE
To evaluate the influence of stroke volume variation (SVV)-based goal-directed therapy (GDT) on splanchnic organ functions and postoperative complications in orthopedic patients.
METHODS
Eighty patients scheduled for major orthopedic surgery under general anesthesia were randomly allocated
OBJECTIVE
To assess the effect of perioperative goal-directed fluid therapy (GDFT) on clinical outcomes in elective colorectal resection.
METHODS
A total of 42 patients undergoing elective colorectal resection between March 2013 and December 2014 were recruited prospectively. GDFT was administrated
While many agents have been developed to aid in weight loss, few have withstood critical assessment of safety and efficacy. Weight loss agents are held to a higher standard for safety and tolerability than medications for other conditions, because they are often used by otherwise healthy individuals
BACKGROUND
The incidence of obesity is increasing; this is of major concern, as obesity is associated with cardiovascular disease, stroke, type 2 diabetes, respiratory tract disease, and cancer.
OBJECTIVE
This evaluation is of a Phase II clinical trial with tesofensine in obese
OBJECTIVE
A randomized controlled trial was conducted to test the hypothesis that there is no difference in complications in patients receiving intravenous (iv) water and electrolyte, based on either stroke volume or clinical indicators at bowel surgery.
METHODS
Eligible patients were randomized
OBJECTIVE
To develop and evaluate an individualized fluid therapy in the elderly patients with coronary heart disease undergoing gastrointestinal surgery.
METHODS
In this prospective study, 60 coronary heart disease patients undergoing gastrointestinal surgery were included in the First Affiliated
UNASSIGNED
The aim of this study is to investigate the clinical effect of goal-directed fluid therapy in elderly patients with radical resection of bladder cancer.
UNASSIGNED
Seventy-six elderly patients with radical resection of bladder cancer were selected from October 2012 to October 2014 and
BACKGROUND
In this study, our objective was to determine whether a perioperative hemodynamic protocol based on noninvasive cardiac output monitoring decreases the incidence of postoperative complications and hospital length of stay in major abdominal surgery patients requiring intensive care unit
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