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folic acid/neoplasms
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Conjugates of noscapine and folic acid and their use in treating cancer
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FIELD OF THE INVENTION
The present invention relates to novel methods and compositions for treating primary and metastatic cancers and other proliferative disorders. These methods and compositions use conjugates of noscapine or noscapine analogs with folic acid or folic acid analogs. These
Chlorin e6-folic acid conjugate, preparation method thereof, and a pharmaceutical composition for the treatment of cancer comprising the same
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This application is U.S. National Phase of International Application No. PCT/KR2009/002276, filed Apr. 29, 2009, designating the United States. The International Application was filed in the Korean language and has not been published as of the filing date of the present application. The Korean
Composition for reducing oxidative stress and/or side effects occurring during cancer chemotherapy or improving nutritional status during cancer chemotherapy
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CROSS REFERENCE TO RELATED APPLICATION
This application is a national stage of international application No. PCT/JP2009/050020 filed on Jan. 6, 2009, which also claims priority under 35 USC 119 to Japanese Patent Application No. 2008-001801 filed Jan. 9, 2008, the entire content of which are
Multi-enzyme bioreactor therapy for cancer
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Field
This invention relates to a device and method for the removal of selected amino acids and folates from a fluid such as blood.
State of the Art
Noncancerous cells can synthesize nonessential (dispensable) amino acids when they are not available in an animal's blood. However, certain tumor cells
Amine derivatives of folic acid analogs
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TABLE OF CONTENTS
1. Field of the Invention
2. Background of the Invention
2.1 Derivatives of Methotrexate and Aninopterin
2.2 Covalent Attachment of Methotrexate To Antibody Molecules
3. Summary of the Invention
4. Brief Description of the Figures
5. Definitions
6. Detailed Description of the
Composition of detection agents for epithelial tumour cells and preparation method therefor
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RELATED APPLICATIONS
The present application is National Phase of International Application No. PCT/CN2012/087880 filed Dec. 28, 2012, and claims priority from Chinese Application No. 201110449270.7 filed Dec. 29, 2011.
FIELD OF THE INVENTION
The invention relates to a detecting agent composition,
Nanoparticles for cytoplasmic drug delivery to cancer cells
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates generally to nanoparticles that are used to deliver drugs into the cytoplasm of cancer cells and, more specifically, to the rapid delivery of the drugs by nanoparticles that have an inner core containing an anticancer drug
Targeted delivery and prodrug designs for platinum-acridine anti-cancer compounds and methods thereof
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FIELD OF THE INVENTION
The present invention relates to new platinum containing compounds that show increased potency and efficacy in vitro and in vivo against certain types of cancer and compounds, compositions containing said compounds, and methods of delivering those compounds to treat these
N-[N-(tetrahydropyrido[2,3-D]pyrimidinylmethyl)-aminomethylbenzo yl]glutamic acid derivatives as neoplastic growth inhibitors
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The present invention pertains to the individual diastereomers and to the diastereomeric mixture of glutamic acid derivatives of the formula: ##STR1## in which:
R.sup.1 is hydrogen, alkyl of 1 to 6 carbon atoms, or alkanoyl of 1 to 6 carbon atoms;
R.sup.2 is hydrogen or a carboxy protecting
Micronutrient formulations for radiation applications
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BACKGROUND OF THE INVENTION
Field of the Invention
This invention relates to a use of micronutrient formulations to reduce the effects of radiation on humans.
Description of the Related Art
Ionizing radiation (X-rays and gamma rays) has proven to be a double-edged sword in clinical Medicine since
Nutrient compositions and methods for enhanced effectiveness of the immune system
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This invention relates generally to promoting the healing process of physiological disorders or diseases and, more specifically to nutrient compositions that promote the effectiveness or efficiency of the immune system.
Physiological disorders and diseases affect millions of individuals each year.
Nutrient compositions and methods for enhanced effectiveness of the immune system
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This invention relates generally to promoting the healing process of physiological disorders or diseases and, more specifically to nutrient compositions that promote the effectiveness or efficiency of the immune system.
Physiological disorders and diseases affect millions of individuals each year.
Nutritional preparation comprising ribose and medical use thereof
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The invention is related to nutritional, pharmaceutical or dietetic preparations that comprise ribose or folic acid or functional analogs thereof and the use of these compositions in the prevention or treatment of specific diseases that are related to disorders or insufficiencies of total nucleotide
Nutritional preparation comprising ribose and medical use thereof
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The invention is related to nutritional, pharmaceutical, or dietetic preparations that comprise ribose or folic acid or functional analogs thereof and the use of these compositions in the prevention or treatment of specific diseases that are related to disorders or insufficient of total nucleotide
Nutritional methyl supplements change DNA methylation and related characteristics of mammalian offspring
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FIELD OF THE INVENTION
The invention relates generally to a dietary supplement that increases DNA methylation, methods for altering the phenotype of offspring using the supplement, and methods for inhibiting retroviral expression using the supplement. The invention also relates to an animal model
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