galium/tyrosine

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Inhibition of experimental autoimmune encephalomyelitis by a tyrosine kinase inhibitor.

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Migration of lymphocytes from the blood into the brain is a critical event in the pathogenesis of experimental autoimmune encephalomyelitis. Lymphocyte adhesion to brain endothelium is the first step in lymphocyte entry into the central nervous system, leading subsequently to myelin damage and

Amyloid precursor protein mediates monocyte adhesion in AD tissue and apoE(-)/(-) mice.

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Amyloid precursor protein (APP) is a type 1 integral membrane protein, which is highly conserved and ubiquitously expressed. Numerous data suggest it functions in cellular adhesion. For example, APP binds components of the extracellular matrix to propagate intracellular signaling responses. In order

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