1-Cyano-2-hydroxy-3-butene (CHB), an aliphatic nitrile found in cruciferous vegetables, causes a two- and sevenfold elevation in reduced glutathione (GSH) in rat liver and pancreas, respectively, after oral administration of 200 mg/kg. While this dose is also associated with pancreatotoxicity, a
The effect of dietary polyunsaturated fatty acids (PIFA) upon the content of reduced glutathione (GSH) of the kidney was studied in 32 male Wistar rats. Two equal size groups were fed diets supplemented with either 10% or 18% corn oil. Sixteen hours before death, half of each experimental group was
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