The chemical composition of total alkaloids from leaves and roots of Guiera senegalensis was investigated. Three beta-carboline alkaloids were purified: in addition to harman and tetrahydroharman, known in roots and leaves, harmalan (dihydroharman) was isolated for the first time from roots of
Despite the availability of anticancer drugs, breast cancer remains the most death-causing tumor-related disease in women. Hence, there is a need for discovery and development of efficient alternative drugs, and sources such as plants need to be explored. In this study, antioxidant capacities and
Guiera senegalensis J. F. Gmelin (Combretaceae) leaves are used in African traditional medicine for gastrointestinal disorders, cough and topically for wound healing. This paper regards the evaluation of antiradical, antielastase, antimicrobial, genotoxic and antimutagenic activities of the leaf
BACKGROUND
Malignant diseases are responsible of approximately 13% of all deaths each year in the world. Natural products represent a valuable source for the development of novel anticancer drugs. The present study was aimed at evaluating the cytotoxicity of a naphtyl butanone isolated from the
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