guiera senegalensis/antifungal

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Guieranone A, a naphthyl butenone from the leaves of Guiera senegalensis with antifungal activity.

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A new methoxylated naphthyl butenone, guieranone A (1), was isolated from the leaves of Guiera senegalensis. Its structure was elucidated as (2E)-1-(1,3,6,8-tetramethoxy-2-naphthyl)but-2-en-1-one, on the basis of spectroscopic data. Also isolated were two known naphthopyrones,

Ethnopharmacological Uses, Phytochemistry and Pharmacological Activities of Guiera senegalensis J.F. Gmel. (Combretaceae)

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Ethnopharmacological relevance: Guiera senegalensis J.F. Gmel. (Combretaceae), commonly known as "Gubeish" in Sudan, is a small shrub abundant in semi-desert areas of the Sudano-Sahelian zone. It is widely used in African traditional

In vitro evaluation of novel antiviral activities of 60 medicinal plants extracts against hepatitis B virus.

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Currently, >35 Saudi Arabian medicinal plants are traditionally used for various liver disorders without a scientific rationale. This is the first experimental evaluation of the anti-hepatitis B virus (HBV) potential of the total ethanolic and sequential organic extracts of 60 candidate medicinal

Harmine is a potent antimalarial targeting Hsp90 and synergizes with chloroquine and artemisinin.

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Previous studies have shown an antimalarial effect of total alkaloids extracted from leaves of Guiera senegalensis from Mali in West Africa. We independently observed that the beta-carboline alkaloid harmine obtained from a natural product library screen inhibited Plasmodium falciparum heat shock

[Anti-infective phytotherapies of the tree-savannah, Senegal (occidental Africa). III: A review of phytochemical substances and the antimicrobial activity of 43 species].

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A review has been made of the ethnobotanical and pharmacological data of 43 medicinal plants of the tree-savannah used by the Diola against infectious diseases. The traditional use of ten plants can be explained by pharmacologically active principles: Adansonia digitata, Azadirachta indica, Carica

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