hepatic encephalopathy/obesity

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Modulation of Gut Microbiota by Rifaximin in PD Patients

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Gut microbiota is the largest microorganisms pool in the human body. The physiological roles of gut microbiota for digestion, metabolism, immune homeostasis, GI-tract infection prevention and anti-inflammation. The very first colonized gut microbiota of infant are from maternal vaginal fluid. Gut

Microvesicles and Monocytes to Predict Mortality of Patients With Cirrhosis

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Natural history of cirrhosis Cirrhosis is the end stage form of chronic liver disease. It is estimated that 200,000 to 500,000 people in France have cirrhosis. Cirrhosis is responsible for more than 170,000 deaths per year in Europe. The main causes of cirrhosis include excessive alcohol

Fecal Microbiota Transplant (FMT) to Induce Weight Loss in Obese Subjects

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Recently, accumulating evidence supports a role of the enteric microbiota in the pathogenesis of obesity-related insulin resistance. Obesity is associated with changes in the composition of the intestinal microbiota, and the obese microbiome appears to be more efficient in harvesting energy from the

Hepatic Urea Nitrogen Handling in Patients With NASH

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NAFLD is the most common cause of chronic liver disease in the western world affecting 10-30% of the general population. It is strongly associated with the metabolic syndrome caused by overweight and obesity. NAFLD is a spectrum of liver disease ranging from steatosis (hepatocytic fat accumulation

Evolution and Clinical Outcomes in Patients Undergoing Liver Transplantation

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This study was carried out at the Alfa Institute of Gastroenterology, Hospital of Clinics, Universidade Federal of Minas Gerais (UFMG). The research protocol was approved by the UFMG Ethics Committee. Patients with indication for liver transplantation, aged over 20 years who regularly attended the

Liver Transplantation in Alcoholic Hepatitis

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This is a open prospective multicenter study. Nineteen liver transplant units in Spain will take part in it. Inclusion criteria for patients: 1. Diagnosis of alcoholic hepatitis (liver biopsy will be advisable). 2. First episode of clinical decompensation of alcoholic liver disease (defined as

Role of Methane in Glycemic Control

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Pre-diabetes is defined by impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT) and affects more than 40% of US adults. While glycemic dysregulation and insulin resistance are central to the progression from pre-diabetes to diabetes, obesity also plays a key role. Research has

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