hepatitis a/triglyceride

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Modulation of triglyceride and cholesterol ester synthesis impairs assembly of infectious hepatitis C virus.

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In hepatitis C virus infection, replication of the viral genome and virion assembly are linked to cellular metabolic processes. In particular, lipid droplets, which store principally triacylglycerides (TAGs) and cholesterol esters (CEs), have been implicated in production of infectious virus. Here,

Effect of calcium lactate supplementation on cholesterol concentration in patients with hyperlipidaemia and previous viral hepatitis: a preliminary report.

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The aim of the study was to estimate the effect of calcium supplementation on cholesterol concentrations in patients with hyperlipidaemia and previous viral hepatitis. The study comprised 43 patients, aged 28 to 82 years (21 with type 2 hyperlipidaemia). The control group included 22 healthy

Lipid profile in children with acute viral hepatitis A.

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BACKGROUND Most of the knowledge about lipid parameters in acute hepatitis is originated from adult studies. In this study, the authors investigated lipid profile of children with acute hepatitis A (AVH) at diagnosis and recovery in order to observe the behavior of lipid parameters in such

[The biochemical indices of the blood serum in experimental hepatitis A in tamarins].

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Serum biochemical parameters were studied in 42 healthy wild-caught adult tamarins (S. mystax), males and females, to determine the normal values. Blood samples were drawn repeatedly, and the serum was tested for aspartate aminotransferase, alanine aminotransferase, isocitric dehydrogenase, serum

Helicobacter pylori and hepatitis A virus infections and the cardiovascular risk profile in patients with diabetes mellitus: results of a population-based study.

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OBJECTIVE The objective of this study was to investigate the associations of sero-positivity for Helicobacter pylori (HP) and hepatitis A virus infection (HAV) with prevalence of cardiovascular diseases (CVD) and CVD-risk markers in a large population-based sample of patients with diabetes mellitus

The alanine aminotransferase to triglycerides ratio as a marker to identify nonalcoholic fatty liver disease.

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OBJECTIVE The aim of this study was to determine whether the alanine aminotransferase to triglycerides (ALT/TGL) ratio is useful to identify nonalcoholic fatty liver disease (NAFLD) in asymptomatic overweight and obese women. METHODS Asymptomatic overweight and obese women aged 20-65 years were

Hepatitis A Associated with Chylothorax: An Uncommon Presentation of a Common Infection.

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Extra-hepatic manifestations have seldom been described with hepatitis A, which usually manifests as mild hepatic dysfunction. We report a 3-year-old boy presenting with 3 days of fever, vomiting, abdominal distention and scleral icterus. On examination, he had tachypnea, hepatosplenomegaly, ascites

Release of Infectious Hepatitis C Virus from Huh7 Cells Occurs via a trans-Golgi Network-to-Endosome Pathway Independent of Very-Low-Density Lipoprotein Secretion.

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The release of infectious hepatitis C virus (HCV) particles from infected cells remains poorly characterized. We previously demonstrated that virus release is dependent on the endosomal sorting complex required for transport (ESCRT). Here, we show a critical role of trans-Golgi network

Hepatocyte nuclear factor 4α and downstream secreted phospholipase A2 GXIIB regulate production of infectious hepatitis C virus.

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Hepatitis C virus (HCV) is a major cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma in humans. The life cycle of HCV is closely associated with the metabolism of lipids, especially very-low-density lipoprotein (VLDL) in hepatocytes. Hepatocyte nuclear factor 4α (HNF4α), the

Alcoholic Hepatitis: A Common Disease with Uncommon Presentation

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Alcoholic liver disease is one of the leading causes of hepatitis, cirrhosis, liver failure, and hepatic carcinoma. Alcoholic hepatitis refers to the acute onset of symptomatic hepatitis. We describe a patient who presented with alcoholic hepatitis with direct hyperbilirubinemia, elevated alkaline

Association between the TIMD4-HAVCR1 variants and serum lipid levels, coronary heart disease and ischemic stroke risk and atorvastatin lipid-lowering efficacy.

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Little is known about the association of the TIMD4 (T-cell immunoglobulin and mucin domain 4 gene)-HAVCR1 (hepatitis A virus cellular receptor 1) variants and lipid metabolism, the risk of coronary heart disease (CHD) and ischemic stroke (IS). The present study aimed to determine the TIMD4-HAVCR1

Nonalcoholic fatty liver disease in asymptomatic Brazilian adolescents.

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OBJECTIVE To evaluate the prevalence and clinical characteristics of Nonalcoholic fatty liver disease (NAFLD) among asymptomatic Brazilian adolescents. METHODS Transversal observational study included asymptomatic adolescents with central obesity from private and public schools in Salvador-Bahia,

Liver damage in severely obese patients: a clinical-biochemical-morphologic study on 1,000 liver biopsies.

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BACKGROUND Preoperative clinical and biochemical data and intraoperative liver biopsy of 1,000 obese patients submitted to biliopancreatic diversion (BPD) were analyzed, and correlations investigated. METHODS Of 2,645 patients submitted to BPD between May 1976 and November 2002, the last 1,000

Correlation of hepatitis C and prostate cancer, inverse correlation of basal cell hyperplasia or prostatitis and epidemic syphilis of unknown duration.

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OBJECTIVE The accuracy of prostate specific antigen (PSA) to detect prostate cancer has not yet been determined. Autopsy evidence suggests one-third of men have evidence of prostate cancer. Correlation between prostate cancer and sexually transmitted infection is indeterminate. METHODS A

[Cholestatic-type hepatitis in childhood].

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OBJECTIVE The aim of this study was to evaluate the incidence, etiology, clinical evolution and prognosis of cholestatic hepatitis during childhood. METHODS A retrospective study of 145 children hospitalized for acute hepatitis between December 1983 and September 1996 were studied. Cholestatic

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