hernia/hypoxia

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Hypoxia inducible factor 2α (HIF2α/EPAS1) is associated with development of pulmonary hypertension in severe congenital diaphragmatic hernia patients.

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We show that hypoxia inducible factor 2α (HIF2α) is highly expressed in patients with pulmonary hypertension (PH). HIF2α is expressed in every patient with congenital diaphragmatic hernia, while only half of the controls express HIF2α. Our data suggest that HIF2α is a link between hypoxia and the

Expression of hypoxia-inducible factors, regulators, and target genes in congenital diaphragmatic hernia patients.

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Congenital diaphragmatic hernia (CDH) is associated with lung hypoplasia and pulmonary hypertension and has high morbidity and mortality rates. The cause and pathophysiology of CDH are not fully understood. However, impaired angiogenesis appears to play an important role in the pathophysiology of

Relation between arterial hypoxemia and plasma eicosanoids in neonates with congenital diaphragmatic hernia.

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Pulmonary hypertension is a major source of morbidity and mortality in infants born with congenital diaphragmatic hernia (CDH). Increased pulmonary vascular resistance leads to right-to-left shunting, which is evident as decreases in the PaO2 measured in postductal arterial blood. Thromboxane A2

[Efficacy of nifedipine on refractory hypoxemia associated with diaphragmatic hernia in the newborn infant. Apropos of a case].

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A 3,200 g birth weight, 38-week gestational age neonate developed very severe persistent pulmonary hypertension following surgical repair of a left diaphragmatic hernia. Despite administration of dopamine, dobutamine, and tolazoline, a significant alveolar-arterial oxygen difference (660 mmHg) was

[Treatment of anoxia in the newborn in relation to hernia of the diaphragmatic cupula].

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[Postero-lateral hernia of the left diaphragmatic coupola in the newborn. Recovery from refractory hypoxemia with nifedipine].

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Transdiaphragmatic Hernia and Hypoxemia during Colonoscopy.

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Traumatic rupture of the diaphragm and herniation of the liver.

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Injuries that result in a sudden increase in intra-abdominal pressure may cause a diaphragmatic tear and visceral herniation. Right-sided tears are significantly less likely than left-sided tears because of the protective effect of the liver. When diaphragmatic elevation persists in a post-trauma

Intraoperative management of a patient with a chronic, previously undiagnosed traumatic diaphragmatic hernia.

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Traumatic diaphragmatic hernia (TDH) occurs in approximately 5% of hospitalized motor vehicle accident victims and 10% of victims of penetrating chest injury. Although most such injuries are diagnosed at the time of initial trauma, approximately 10% become apparent only months or years later. The

Anesthesia for patients with diaphragmatic hernia and severe dyspnea.

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Problems facing a patient with severe dyspnea secondary to diaphragmatic herniation are hypoxia, hypercarbia and respiratory acidosis, and cardiovascular instability. It is easy to precipitate a crisis in these patients during anesthetic induction as a result of stress, bad positioning, induction of

Pulmonary vascular abnormalities in congenital diaphragmatic hernia.

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Persistent pulmonary hypertension poses a significant problem to the surgeon managing an infant with congenital diaphragmatic hernia. It is likely that a number of abnormalities contribute to this pathophysiologic entity. These include: (1) in the hypoplastic lung the overall cross-sectional area of

Risk factors for spinal anesthesia in preterm infants undergoing inguinal hernia repair.

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OBJECTIVE To investigate the risk factors and incidence of perioperative adverse effects from unsupplemented spinal anesthesia in preterm infants. Times to resumption of oral feeding and to home discharge were also evaluated. METHODS Perioperative data were collected prospectively for all preterm

High-frequency oscillation for persistent fetal circulation after repair of congenital diaphragmatic hernia.

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A female neonate who had been diagnosed as having congenital diaphragmatic hernia by ultrasonography was delivered by cesarean section. After the hernia was repaired, she developed hypoxemia and hypercapnia, probably due to persistent fetal circulation (PFC). Neither conventional mechanical

Pathophysiology and management of congenital posterolateral diaphragmatic hernias.

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Twelve neonates with foramen of Bochdalek hernias were treated at the Medical College of Virginia Hospitals during a recent four-year period. The clinical material supports the concept that bilateral hypoplastic lungs are fundamental in producing a morbid vicious cycle with respiratory and metabolic

Pneumothorax during laparoscopic totally extraperitoneal inguinal hernia repair -A case report-.

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We experienced an extremely rare complication during performance of laparoscopic totally extraperitoneal (TEP) inguinal hernia repair for a 57-year-old healthy man. About 50 minutes after CO(2) insufflation, the patient developed tachycardia, hypoxemia, hypercapnia and an increased airway pressure.

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