histone/obesity

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Phosphorylation of histones and uses thereof

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FIELD OF THE DISCLOSURE The disclosure is generally related to compositions and methods for detecting phosphorylated histones and determining activities of kinases regulating such phosphorylation. Also disclosed are methods of disease diagnosis, prognosis and therapy selection based on such

Inhibitors of histone deacetylase

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FIELD OF THE INVENTION The present invention relates generally to inhibitors of histone deacetylase and to methods of making and using them. These compounds are useful for treating, alleviating, and/or preventing metabolic disorders such as dyslipidemias, lipodystrophies, liver diseases associated

Thienopyrroles as histone demethylase inhibitors

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CROSS-REFERENCE TO RELATED APPLICATIONS This application is a U.S. National Phase application, filed under 35 U.S.C. .sctn. 371(c), of International Application No. PCT/IB2015/001953, filed Sep. 4, 2015, which claims priority to, and the benefit of, European Patent Application No. 14183755.9, filed

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