Present study is an attempt to investigate plausible mechanism involved behind antidiabetic activity of standardized Houttuynia cordata Thunb. extract in streptozotocin-induced diabetic rats. The plant is used as a medicinal salad for lowering blood sugar level in North-Eastern parts of India. Oral
OBJECTIVE
To explore the effects of Houttuynia Cordata Thumb (HCT Yu Xing Cao) on expression of transforming growth factor-beta1 (TGF-beta1) and bone morphogenetic protein-7 (BMP-7) in the renal tissues of diabetic rats.
METHODS
The diabetic rats induced by intravenous injection of
Development of a therapy providing protection from, or reversing gentamicin-sulfate (GS)-induced oxidative stress and nephrotoxicity would be of great clinical significance. The present study was designed to investigate the protective effects of Houttuynia cordata Thunb. (HC) against gentamicin
OBJECTIVE
The anti-glycative and anti-oxidative effects from Houttuynia cordata leaves aqueous extract (HCAE) in heart and kidney of diabetic mice were examined.
METHODS
HCAE, at 1 or 2 %, was supplied in drinking water for 8 weeks. Plasma glucose and blood urea nitrogen (BUN) levels and creatine
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