hypercholesterolemia/albumin

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Association between ischemia-modified albumin, lipids and inflammation biomarkers in patients with hypercholesterolemia.

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OBJECTIVE The aim of this study was to evaluate the association between ischemia-modified albumin (IMA), lipids and inflammation biomarkers in patients with hypercholesterolemia, and the possible involvement of IMA in atheromatous plaque development and oxidative stress. METHODS Glucose, total

Effect of hypercholesterolemia on transendothelial EBD-albumin permeability and lipid accumulation in porcine iliac arteries.

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Hypercholesterolemia is associated with increased cardiovascular mortality and is known to promote the advancement of atherosclerotic lesions in experimental animal models. Juvenile swine were fed a normal or high-cholesterol diet, and the transendothelial macromolecular permeability of the external

[Effect of hypercholesteremia on vascular endothelial function and albumin excretion rate in patients with diabetes mellitus].

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Tissue-type plasminogen activator (tPA) is an endothelium-derived vasoactive substance which is released to the blood stream by exercise, blood occlusion, and desmopressin (DDAVP). The increased capacity of the plasma tPA level raised by these factors is thought to reflect in vivo endothelial

Downregulation of hepatic albumin mRNA in response to induced hypercholesterolemia in rabbits.

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Albumin gene expression was studied in rabbits fed on a cholesterol-rich diet for up to 16 weeks. Livers from experimental animals showed extensive lipid deposition. Hepatic albumin mRNA abundance decreased along the treatment to very low levels after 16 weeks. An 8-fold decrease in the rate of

The causal role of plasma albumin deficiency in experimental nephrotic hyperlipemia and hypercholesteremia.

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Progressive microcirculatory changes caused by hypercholesterolemia in rats.

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The progressive microcirculatory changes caused by hypercholesterolemia were studied in the rat cremaster model by use of intravital microscopy. Male Sprague-Dawley rats were fed either a normal chow diet or a chow diet supplemented with 1% cholesterol and 0.5% cholic acid for 1, 3, or 5 wk before

Extracorporeal treatment of familial hypercholesterolemia with monoclonal antibodies to low-density lipoprotein.

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Plasma exchange (PE) is considered the most effective nonsurgical treatment modality for the reduction of low-density lipoprotein (LDL) in patients with familial hypercholesterolemia (FH). However, the concomitant reduction of high-density lipoprotein (HDL) and the necessity and cost of using blood

Transgenic expression of dominant-active IDOL in liver causes diet-induced hypercholesterolemia and atherosclerosis in mice.

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BACKGROUND The E3 ubiquitin ligase inducible degrader of the low-density lipoprotein receptor (IDOL) triggers lysosomal degradation of the low-density lipoprotein receptor. The tissue-specific effects of the IDOL pathway on plasma cholesterol and atherosclerosis have not been

Hypercholesterolemia and glomerular diseases in urinary screening of school children.

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Although hypercholesterolemia frequently accompanies nephrotic syndrome, high serum total cholesterol (TC) levels are occasionally seen in children with non-nephrotic glomerular diseases. However, little is known of the significance, if any, of these elevated serum TC levels in non-nephrotic

Protective effect of tannins from Ficus racemosa in hypercholesterolemia and diabetes induced vascular tissue damage in rats.

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OBJECTIVE To evaluate the protective effect of tannins from Ficus racemosa (F. racemosa) on the lipid profile and antioxidant parameters in high fat meal and streptozotocin induced hypercholesteremia associated diabetes model in rats. METHODS The crude tannin fraction was separated from the acetone

Reduction of albumin excretion rate in normotensive microalbuminuric type 2 diabetic patients during long-term simvastatin treatment.

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OBJECTIVE To study the long-term effects of simvastatin on urinary albumin excretion rate (AER) in normotensive microalbuminuric type 2 diabetic patients with hypercholesterolemia. METHODS A total of 19 normotensive microalbuminuric hypercholesterolemic type 2 diabetic patients entered a

Prevalence of increased albumin excretion rate in young saudi adults.

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BACKGROUND Albuminuria is an important risk predictor of chronic kidney disease and cardiovascular disease. In this study, we aim to evaluate the prevalence of increased urinary albumin excretion (UAE) rate amongst a subgroup of young Saudi army/navy recruits. METHODS 2,000 Saudi military recruits

Elevated albumin excretion in nonmodulating essential hypertensive patients.

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Nonmodulating (NM) essential hypertensives are characterized by abnormal renal and aldosterone responses to angiotensin II. Recently, hyperinsulinemia, hypercholesterolemia, and an increased prevalence of family history of hypertension and myocardial infarction have been shown in NM hypertensives.

Hypercholesterolemia aggravates radiocontrast nephrotoxicity: protective role of L-arginine.

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It is well known that the radiocontrast-induced ARF depends on risk factors often associated with compromised renal circulation. Since studies have shown that endothelium-dependent vasodilation is impaired in hypercholesterolemia (HC), we studied the effect of radiocontrast (RC) administration (6

Non-steady-state kinetics of low density lipoproteins in man: studies after plasma exchange in healthy subjects and patients with familial hypercholesterolaemia.

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Five patients with heterozygous familial hypercholesterolaemia (FH), one patient with non-familial hypercholesterolaemia, and four healthy normals were treated with plasma exchange (PE). In order to achieve a non-steady-state situation with low plasma cholesterol levels, PE was performed twice in

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