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hypercholesterolemia/phosphatase
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5 results
Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome
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Noonan syndrome (NS) is a relatively frequent autosomal dominant disorder characterised by facial dysmorphic features, heart defects, developmental delay, and short stature. This syndrome is mostly caused by gain-of-function mutations in the PTPN11 gene, encoding tyrosine phosphatase. The
The Very Large Database of Lipids (VLDL)
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REGISTRATION & STATUS OF VLDL STUDIES
- VLDL-1A: Friedewald Estimated versus Directly Measured Low-Density Lipoprotein Cholesterol and Treatment Implications (abstract presented; manuscript published; citation provided below)
- VLDL-1B: Comparison of a Novel Method vs the Friedewald Equation for
Efficacy And Safety Of Smoking Cessation With Varenicline Tartrate In Diabetic Smokers: (DIASMOKE)
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INTRODUCTION
Cigarette smoking harms nearly every system of the human body, thus causing a broad range of diseases, many of which are fatal. In particular, cardiovascular disease (CVD) is the most important cause of death in those who smoke (1). Both diabetes mellitus and cigarette smoking are
Comparison of Simvastatin Versus Simvastatin/Ezetimibe on Small Dense Low -Density Lipoprotein (LDL)
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Hypercholesterolemia is a major risk factor for atherosclerosis and coronary heart disease (CHD).[1] Epidemiological and clinical studies have demonstrated that aggressive lowering of low-density lipoprotein cholesterol (LDL-C) reduces morbidity and mortality in patients with or without CHD.[1-3]
Carotid Atherosclerosis Regression at Magnetic Resonance Assessment.
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FULL PROTOCOL
1.0 SYNOPSIS The primary objective of this randomized, double blind, placebo controlled pilot study is to determine if therapies aimed at lowering LDL cholesterol (HMGCoA reductase inhibitor - simvastatin) or increasing HDL cholesterol (Niaspan) will induce regression of carotid
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