OBJECTIVES:
- Compare the change in depression severity in cancer patients with mild to moderate depression treated with sertraline vs Hypericum perforatum.
- Compare the severity of somnolence, nausea, and insomnia in patients treated with these regimens.
- Compare the impact of these regimens on
OBJECTIVES:
- Determine the effect of Hypericum perforatum (St. John's Wort) on the pharmacokinetic clearance of docetaxel in patients with unresectable solid tumors.
- Determine the effect of Hypericum perforatum on the production and plasma concentrations of M4-C13-hydroxydocetaxel in these
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