Canagliflozin is an SGLT2 inhibitor used for the treatment of type 2 diabetes mellitus. Studies were conducted to investigate the mechanism responsible for renal tubular tumors and pheochromocytomas observed at the high dose in a 2-year carcinogenicity study in rats. At the high dose (100mg/kg) in
Morgagni's Syndrome is a polyglandular endocrine syndrome, occurring almost exclusively in the female sex. It is characterized of the classical triad: internal frontal hyperostosis, obesity, virillism, and often accompanied by an old-age type of diabetes. In itself the hyperostosis is of little
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