Methods:
A prospective study for 1 year starting 1/1/2019 to 1/1/2020. A total 74 patients with normal renal function .admitted for thyroidectomy. Preoperative serum calcium, magnesium, phosphate and vitamin D level all checked. Postoperatively corrected serum calcium, magnesium and phosphate level
The design consists in a five-periods, two-treatments, open-label, randomized, crossover study with blind end-point evaluation.
Patients will come for an inclusion visit and will receive treatment with 0.5 µg/day alfacalcidol for 4 weeks (28±3 days, run-in). They will be instructed to maintain
Objectives
The primary objective of this study is to evaluate the skeletal effects of hormone replacement therapy with HPTH in hypoparathyroidism.
Study Population
This study will enroll up to 69 subjects with physician-diagnosed hypoparathyroidism.
Design
This study will treat hypoparathyroid
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