ilex pubescens/thrombosis

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Botany, traditional uses, phytochemistry, pharmacology and toxicology of Ilex pubescens Hook et Arn.

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Ilex pubescens (I. pubescens), which is well known in Chinese as Mao-Dong-Qing, is widely used in traditional Chinese medicine. This plant is distributed in the wild in southern China, and the roots and stems are used for clearing heat, detoxifying, activating blood circulation and

[Ilexonin A may be a slow calcium channel blocker].

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Ilexonin A is an effective compound isolated from Ilex pubescens Hook. et Arn. It has been used in the clinic to treat cardiovascular diseases such as cerebral embolism and myocardial infarction. Experimental studies have shown that it inhibited thrombosis, platelet adhesion, and platelet

Specific inhibiting effects of Ilexonin A on von Willebrand factor-dependent platelet aggregation under high shear rate.

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BACKGROUND Ilexonin A (IA), purified from the Chinese herbal medicine Maodongqing (Ilex pubescens Hook, et Arn) has been commonly used in south China to treat thrombotic disorders. In this study, we aimed to study the inhibiting effects and mechanism of IA on von Willebrand factor (vWF)-dependent

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