indole/breast neoplasms

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Effectiveness of DIM Supplements to Increase 2-OHE1/16 Ratio

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The purpose of this study was to evaluate the effectiveness of supplementation with 3,3´-Diindolylmethane (DIM) to increase the urinary ratio of estrogen metabolites 2OHE1:16alphaOHE1 (RMEU) in women at risk of breast cancer to contribute to generate a tool of early prevention of this

Plant Extracted Natural Compounds Impact on Stage IV Breast Cancer Survival Time and Remission.

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OBJECTIVES: To utilize multiple naturally-occurring bioalkaloids, bioactive "compounds of interest" from multiple sources, to influence prostate, breast, and uterine cancer pathways in cancer patients and cancer patients in remission. Other cancer types may be applicable. To utilize specific

Indole-3-Carbinol in Preventing Breast Cancer in Nonsmoking Women Who Are at High Risk For Breast Cancer

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OBJECTIVES: - Determine the safety and tolerability of indole-3-carbinol for the prevention of breast cancer in non-smoking women at high risk for breast cancer. - Determine the pharmacokinetics of this drug in these participants. - Determine the effect of this drug on metabolites of estrogen in

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