isodon/hypersensitivity

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Isodon japonicus inhibits mast cell-mediated immediate-type allergic reactions.

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The effect of aqueous extract of Isodon japonicus Hara (Labiatae) (IJAE) on mast cell-mediated immediate-type allergic reactions was investigated. IJAE inhibited systemic allergic reaction induced by compound 48/80. When IJAE was pretreated at the same concentrations with systemic allergic reaction

Isodon japonicus decreases immediate-type allergic reaction and tumor necrosis factor-alpha production.

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BACKGROUND The immediate-type allergic reaction is involved in many allergic diseases such as asthma, allergic rhinitis and sinusitis. The discovery of drugs for the treatment of immediate-type allergic disease is a very important subject in human health. Isodon japonicus Hara (Labiatae) (IJAE) has

[Studies on immune function of Rabdosia excisa].

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OBJECTIVE To study the immune function of Rabdosia excisa decoction. METHODS Weighting immune organ of mice, and studying the effects on carbon clearance rate in mice, lymphocyte transformation in vitro, the formation of serum hemolysin in mice and delayed hypersensitivity. RESULTS 10 or 20 g/kg

Involvement of Glutathione Depletion in Selective Cytotoxicity of Oridonin to p53-Mutant Esophageal Squamous Carcinoma Cells.

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Oridonin, a diterpenoid compound isolated from traditional Chinese medicine Rabdosia rubescens, has shown antitumor effects to esophageal cancer. However, its molecular mechanism is not fully understood, which limits its clinical application. In the present study, we used RNA-seq analysis to check

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