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3 results
Effects of dietary supplementation with butylated hydroxyanisole, cysteine, and vitamins B on tansy ragwort (Senecio jacobaea) toxicosis in ponies.
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Dried tansy ragwort, which contains pyrrolizidine alkaloids, was fed as 10% of a complete diet to ponies, with and without a mixture of additives. The additives provided a dietary supplement equivalent to 1% cysteine, 0.75% butylated hydroxyanisole, 200 micrograms of vitamin B12/kg of feed, and 5 mg
Effect of dietary Senecio jacobaea and injected Senecio alkaloids and monocrotaline on guinea pigs.
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The chronic toxicity of 10% dietary Senecio jacobaea (SJ) in guinea pigs was studied during a 365-d feeding trial. The SJ plant contains hepatoxic pyrrolizidine alkaloids (PA). The chronic lethal dose (LD100) of SJ for guinea pigs was 1,264 g/kg initial body weight or 526% of initial body weight
Comparative effects of antioxidants on the toxicity of mixed pyrrolizidine alkaloids from Senecio jacobaea in mice.
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The comparative effects of the antioxidants, butylated hydroxyanisole (BHA), ethoxyquin, and cysteine on pyrrolizidine-alkaloid-induced (PA-induced) lethality and acute hepatotoxicity were assessed in female mice. Diets containing 0.75% BHA, 0.25% ethoxyquin, or 1% cysteine were fed to mice for 10 d
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