RESEARCH PLAN
A: Primary aims:
1. Determine the effect of 4 months of oral galactose administration on the level of FSPF in children with steroid resistant FSGS
2. Determine the effect of 4 months of oral galactose administration on the first morning urine protein to creatinine (urine protein:
Patients with resistant FSGS have persistent proteinuria and a high risk of progression to end stage kidney disease (ESKD). A circulating factor that increases glomerular permeability to albumin (Palb) has been detected in over 50% of these patients. While the molecular identity of the factor has
Patients with resistant FSGS have persistent proteinuria and a high risk of progression to end stage kidney disease (ESKD). A circulating factor that increases glomerular permeability to albumin (Palb) has been detected in over 50% of these patients. While the molecular identity of the factor has
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