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juniperus sabina/proteinuria

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PRI-VENT FSGS: Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant

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Recurrent FSGS is a risk factor for graft lost: Recurrence of FSGS can occur rapidly, within minutes of transplantation, and can lead to immediate onset of proteinuria and graft dysfunction. Recurrent FSGS is definitively diagnosed with a kidney biopsy. Early kidney biopsies in recurrent FSGS often

Oral Galactose in Children With Steroid Resistant Nephrotic Syndrome

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RESEARCH PLAN A: Primary aims: 1. Determine the effect of 4 months of oral galactose administration on the level of FSPF in children with steroid resistant FSGS 2. Determine the effect of 4 months of oral galactose administration on the first morning urine protein to creatinine (urine protein:

Effect of Oral Galactose on Focal Segmental Glomerulosclerosis (FSGS) Permeability Factor

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Patients with resistant FSGS have persistent proteinuria and a high risk of progression to end stage kidney disease (ESKD). A circulating factor that increases glomerular permeability to albumin (Palb) has been detected in over 50% of these patients. While the molecular identity of the factor has

Effect of Galactose on Permeblity Factor in Patients With FSGS and CKD Stage 5

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Patients with resistant FSGS have persistent proteinuria and a high risk of progression to end stage kidney disease (ESKD). A circulating factor that increases glomerular permeability to albumin (Palb) has been detected in over 50% of these patients. While the molecular identity of the factor has

Rituximab Treatment of Focal Segmental Glomerulosclerosis

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Focal segmental glomerulosclerosis (FSGS) remains an enigmatic disease despite many years of study. There has been a recent increased incidence of FSGS particularly in African Americans in whom the outcome tends to be worse. In about 30% of patients transplanted for FSGS, the disease recurs and
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