keetia/lactate dehydrogenase

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In vitro antiplasmodial activity of plants used in Benin in traditional medicine to treat malaria.

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OBJECTIVE The aim of the study was to evaluate the in vitro antiplasmodial activity of crude extracts of 12 plant species traditionally used in Benin for the treatment of malaria in order to validate their use. METHODS For each species, dichloromethane, methanol and total aqueous extracts were

In vivo antimalarial activity of Keetia leucantha twigs extracts and in vitro antiplasmodial effect of their constituents.

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BACKGROUND The West African tree Keetia leucantha (Rubiaceae) is used in traditional medicine in Benin to treat malaria. The twigs dichloromethane extract was previously shown to inhibit in vitro Plasmodium falciparum growth with no cytotoxicity (>100µg/ml on human normal fibroblasts). METHODS The

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