keratoconjunctivitis sicca/fever

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Juvenile recurrent parotitis.

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BACKGROUND Juvenile recurrent parotitis (JRP) is a rare, recurrent non-obstructive, nonsuppurative parotid inflammation in young children with a multifactorial etiology. METHODS The records of 12 children with recurrent parotitis were retrospectively reviewed. RESULTS The age of onset ranged from 3

Scanning electron microscopy study of human cornea and conjunctiva in normal and various pathological conditions.

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Relatively few morphological studies on human cornea have been performed due to the difficulty in obtaining material. The specimens may be obtained either by superficial scraping-off, limited to the epithelial layer, or from corneal buttons obtained at keratoplasty. Conjunctiva, on the other hand,

Diurnal and twenty-four hour patterning of human diseases: acute and chronic common and uncommon medical conditions.

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The symptom intensity and mortality of human diseases, conditions, and syndromes exhibit diurnal or 24 h patterning, e.g., skin: atopic dermatitis, urticaria, psoriasis, and palmar hyperhidrosis; gastrointestinal: esophageal reflux, peptic ulcer (including perforation and hemorrhage), cyclic

Sarcoidosis in autoimmune disease.

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Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Sarcoidosis coexisting with connective tissue diseases, once considered rare, complicates various such disorders, including rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, Sjögren's syndrome, and the

[A male case of primary Sjögren's syndrome with interstitial pneumonitis and interstitial tubulo-nephritis in the absence of dry eye and dry mouth: parotid gland MRI is a useful diagnostic method for Sjögren's syndrome].

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Here we report a case of primary Sjögren's syndrome with hilar lymphadenopathy, interstitial pneumonitis and interstitial tubulo-nephritis. A 60-year old man was admitted to our hospital in May 1993 because of general fatigue and fever. He was noted to have hypergammaglobulinemia and had positive

Novel treatments for rare rheumatologic disorders: analysis of the impact of 30 years of the US orphan drug act.

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Rare rheumatologic diseases are a heterogeneous group of conditions associated with high morbidity. As a whole group, rare rheumatologic diseases afflict millions of people demanding for effective therapies. Therefore, we analyzed the impact of the US Orphan Drug Act on the development of

Idiosyncratic toxicity associated with potentiated sulfonamides in the dog.

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Idiosyncratic toxicity to potentiated sulfonamides occurs in both humans and dogs, with considerable clinical similarities. The syndrome in dogs can consist of fever, arthropathy, blood dyscrasias (neutropenia, thrombocytopenia, or hemolytic anemia), hepatopathy consisting of cholestasis or

A retrospective clinical study of canine leishmaniasis in 150 dogs naturally infected by Leishmania infantum.

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The clinical and laboratory findings observed in 150 dogs naturally infected by Leishmania infantum, from a large endemic area of southern Italy, are described. There was a gradual onset of clinical signs and the course of the disease was progressive in almost all the cases. The majority of the dogs

Toxic epidermal necrolysis following morbilli-parotitis-rubella vaccination.

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We present the first reported case of toxic epidermal necrolysis (TEN) caused by morbilli-parotitis-rubella (MPR) vaccine. A 13-year-old girl developed TEN 7 days after she received live, attenuated, triple MPR vaccine. The history of drug intake and any illness was negative. At admission the

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