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l asparaginase/breast neoplasms
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Materials and methods directed to asparagine synthetase and asparaginase therapies
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SEQUENCE LISTING
Incorporated by reference in its entirety herein is a computer-readable nucleotide/amino acid sequence listing submitted concurrently herewith and identified as follows: One 26,355 Byte ASCII (Text) file named "708084ST25.txt," created on May 2, 2011.
BACKGROUND OF THE
Materials and methods directed to asparagine synthetase and asparaginase therapies
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BACKGROUND OF THE INVENTION
Asparagine is a naturally occurring amino acid that is found in many proteins. Asparagine synthetase (ASNS) is involved in asparagine biosynthesis. L-asparaginase (L-ASP) is an enzyme that catabolizes asparagine. L-ASP has been used in the treatment of acute lymphoblastic
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