l hyoscyamine/stomach ulcer

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Studies on peptic ulcer disease with special reference to the effect of l-hyoscyamine.

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The effect of pirenzepine and L-hyoscyamine on gastric emptying and salivary secretion in healthy volunteers.

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Pirenzepine is used in the treatment of peptic ulcer disease as an inhibitor of gastric acid secretion. Recent studies suggest that the mode of action on the stomach may be selectively anticholinergic. The present study was undertaken to compare the effect of pirenzepine on gastric emptying with the

Antacid/anticholinergic, cimetidine, and placebo in treatment of active peptic ulcers.

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Seventy-two patients with duodenal (54) or prepyloric (18) ulcers have taken part in a 12-week double-blind trial. Twenty-four patients received cimetidine, 1 g/day; 24 patients received 10 ml of an antacid suspension (buffering 85 mmol acid) 1 and 3 h after every meal and at bedtime and 0.6 mg

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