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latent tuberculosis/proline

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Structural and biophysical characterization of Rv3716c, a hypothetical protein from Mycobacterium tuberculosis.

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Latent tuberculosis (TB) is the main hurdle in reaching the goal of "Stop TB 2050". Tuberculin skin and Interferon-gamma release assay tests used currently for the diagnosis of TB infection cannot distinguish between active disease and latent tuberculosis infection (LTBI) and hence new and sensitive

PPE17 (Rv1168c) protein of Mycobacterium tuberculosis detects individuals with latent TB infection.

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Latent tuberculosis infection (LTBI) is a clinically distinct category of Mycobacterium tuberculosis (Mtb) infection that needs to be diagnosed at the initial stage. We have reported earlier that one of the Mtb proline-proline-glutamic acid (PPE) proteins, PPE17 (Rv1168c) is associated with stronger
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