leukoaraiosis/obesity

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Metabolically healthy obesity and risk of leukoaraiosis; a population based cross-sectional study.

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Metabolically healthy obese (MHO) individual is known to be defended from the metabolic complications of obesity. Leukoaraiosis, which is commonly detected on brain magnetic resonance imaging (MRI), is now recognized as a risk of stroke, dementia and death. However, the association between MHO and

Silent brain infarcts and leukoaraiosis in young adults with first-ever ischemic stroke.

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BACKGROUND We recently observed that 13% of 1,008 consecutive adults aged 15-49 years with first-ever ischemic stroke had one or more silent brain infarcts (SBIs), and more than 5% presented with leukoaraiosis on CT or MRI. We sought to investigate the features of and risk factors for magnetic

[Cognitive impairment in predialysis stages of chronic kidney disease].

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OBJECTIVE To study the development and progression of cognitive impairment (CI), its risk factors and relationship with vascular-wall remodeling in patients with chronic kidney disease (CKD), stages I-IV. METHODS Fifty-one patients, aged 53±10 years, including 20 with CKD, stages I-II, 20 with CKD,

MRI-defined subcortical ischemic vascular disease: baseline clinical and neuropsychological findings. The LADIS Study.

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BACKGROUND Subcortical ischemic vascular disease (SIVD) is a common, but often overlooked cause of vascular cognitive impairment. Diagnostic research criteria for SIVD are based on magnetic resonance imaging (MRI) findings including substantial white matter lesions (WML) and multiple lacunar

Vascular disease and vascular risk factors in relation to motor features and cognition in early Parkinson's disease.

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The purpose of this study was to examine the relationship between vascular disease (and vascular risk factors), cognition and motor phenotype in Parkinson's disease (PD). Recently diagnosed PD cases were enrolled in a multicenter prospective observational longitudinal cohort study. Montreal

Silent lacunar infarction on magnetic resonance imaging (MRI): risk factors.

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We investigated the risk factors for silent lacunar infarction and etat criblé detected by magnetic resonance imaging (MRI). Previous reports have evaluated white matter hyperintensities (WMHs) and periventricular hyperintensities (PVHs) on T2-weighted images, but have not distinguished between

(Pre)diabetes, brain aging, and cognition.

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Cognitive dysfunction and dementia have recently been proven to be common (and underrecognized) complications of diabetes mellitus (DM). In fact, several studies have evidenced that phenotypes associated with obesity and/or alterations on insulin homeostasis are at increased risk for developing

Longer Duration of Hypertension and MRI Microvascular Brain Alterations Are Associated with Lower Hippocampal Volumes in Older Individuals with Hypertension.

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Hippocampal atrophy is associated with cognitive decline. Determining the clinical features associated with hippocampal volume (HV)/atrophy may help in tailoring preventive strategies.This study was aimed to investigate the association between HV (at visit

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