lipoxygenase/obesity

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Use of 15-lipoxygenase inhibitors for treating obesity

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The invention concerns the treatment of obesity, in particular abdominal visceral obesity. More specifically, the invention concerns the use of selective 15-lipoxygenase (LO) inhibitors for preparing medicines useful in the treatment of obesity, or at least abdominal visceral obesity, and its

Adipocyte-specific constructs and methods for inhibiting platelet-type 12 lipoxygenase expression

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FIELD OF THE INVENTION The present invention is directed to constructs, compositions and methods for modulating expression of platelet-type 12 lipoxygenase (12-LO) in adipose cells, useful for amelioration of obesity and conditions associated therewith. BACKGROUND OF THE INVENTION Obesity has become

Adipocyte-specific constructs and methods for inhibiting platelet-type 12 lipoxygenase expression

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INCORPORATION-BY-REFERENCE OF MATERIAL ELECTRONICALLY FILED Incorporated by reference in its entirety herein is a computer-readable nucleotide/amino acid sequence listing submitted concurrently herewith and identified as follows: One 16.9 kilobyte ASCII (text) file named "SMC 002 US-1 seq_ST25"

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