litsea/leukemia

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Novel cytotoxic chalcones from Litsea rubescens and Litsea pedunculata.

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Two novel flavonoids with chalcone skeleton, together with seven known flavonoids, were isolated from the stem barks of Litsea rubescens and Litsea pedunculata. The structures of the new compounds were elucidated on the basis of spectral methods including IR, UV, 1D and 2D NMR. The new chalcones

The effect of isolancifolide on the apoptosis in HL-60 cells through caspase-8-dependent and -independent pathways.

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Isolancifolide is a compound extracted and isolated from Actinodaphne lancifolia, which is a traditional oriental medicine. To determine whether isolancifolide has therapeutic potential as an anticancer molecule, we assessed its apoptotic effects on HL-60 cells, a human leukemia cell line. Apoptotic

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