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15 results
A new arylbenzofuran derivative functions as an anti-tumour agent by inducing DNA damage and inhibiting PARP activity.
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We previously reported that 7-hydroxy-5, 4'-dimethoxy-2-arylbenzofuran (HDAB) purified from Livistona chinensis is a key active agent. The present study investigated the function and molecular mechanism of HDAB. HDAB treatment of cervical cancer cells resulted in S phase arrest and apoptosis,
Selective downregulation of EGF receptor and downstream MAPK pathway in human cancer cell lines by active components partially purified from the seeds of Livistona chinensis R. Brown.
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Deregulation of protein kinase-mediated signaling events is one of the major causes to malignant transformation. In this work, we tried to purify protein kinase inhibitory activity and antitumor activity from ethanol extracts of the seeds of Livistona chinensis R. Brown (LC), a traditional herb used
[Screening of anti-tumor parts from the seeds of Livistona chinensis and its anti-angiogenesis effect].
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OBJECTIVE
To screen the anti-tumor active parts from the seeds of Livistona chinensis R. Br. and its mechanism of anti-angiogenesis effect.
METHODS
MTT assay and ELISA were used to detect the proliferation and the secretion of vascular endothelial growth factor (VEGF) of chronic myelogenous leukemia
Livistona extract inhibits angiogenesis and cancer growth.
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In a screen for naturally occurring angiogenic inhibitors, we have identified an extract from the seed of the plant Livistona chinensis, which has potent anti-angiogenic and anti-tumor activity. The aqueous extract inhibits the in vitro proliferation of endothelial cells and multiple tumor cell
Rare gain of chromosome 5 in a supratentorial hemispheric paediatric pilomyxoid astrocytoma.
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[Study on the anticancer effects of extracts from roots of Livistona chinensis in vitro].
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OBJECTIVE
To observe the effects of extracts from root of Livistona chinensis on the growth inhibition in seven carcinoma cell lines.
METHODS
The growth inhibition was analyzed by MTT, cell colony and cell growth curve measuremen technique in the stomach carcinoma SGC7901, Lymphocytic leukemia
EHHM, a novel phenolic natural product from Livistona chinensis, induces autophagy-related apoptosis in hepatocellular carcinoma cells.
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Hepatocellular carcinoma (HCC) ranks the second cause of cancer-associated mortality worldwide. In the present study, the effects and mechanisms of a new phenolic natural product E-[6'-(5'-hydroxypentyl)tricosyl]-4-hydroxy-3-methoxycinnamate (EHHM) isolated from Livistona chinensis on the growth of
Antioxidant flavanes from Livistona chinensis.
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Three new flavanes and eight known flavonoids were isolated from the fruits of Livistona chinensis. The structure of the new flavanes were established as 2S,3S-3,5,7,3',5'-pentahydroxyflavane (1), 2R,3R-3,5,6,7,8,4'-hexahydroxyflavane (2) and 2R,3R-3,5,6,7,8,3',5'-heptahydroxyflavane (3),
Antioxidative and hepatoprotective activities of the ethyl acetate fraction separated from the fruit of Livistona chinensis.
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Anti-angiogenic effect of Livistona chinensis seed extract in vitro and in vivo.
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The present study aimed to detect the impact of the ethanol extract of the Livistona chinensis seed (EELC) on angiogenesis in human umbilical vein endothelial cells (HUVECs). A chorioallantoic membrane (CAM) assay was used to detect the anti-angiogenic activity of EELC in vivo. In vitro, the effect
In vitro studies of the dry fruit of Chinese fan palm Livistona chinensis.
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The hot water extract of the dry fruit of Chinese fan palm Livistona chinensis R Br. (LC) has been used in folklore medicine in Southern China for treating various tumors. Our in vitro study showed that the ethanolic extract (LCET) and the hot water extract (LCWE) of LC inhibited HL60 cell growth,
Livistona chinensis seed suppresses hepatocellular carcinoma growth through promotion of mitochondrial-dependent apoptosis.
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The Livistona chinensis seed has been used for centuries to clinically treat various types of cancer. However, the precise mechanism of its anticancer activity remains to be elucidated. In the present study, we evaluated the efficacy of the ethanol extract of Livistona chinensis seed (EELC) against
Livistona chinensis seeds inhibit hepatocellular carcinoma angiogenesis in vivo via suppression of the Notch pathway.
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Livistona chinensis seeds have been used for centuries to clinically treat various types of cancer. Our published data suggest that Livistona chinensis seeds are able to inhibit hepatocellular carcinoma (HCC) growth in vitro and in vivo via promotion of mitochondrial-dependent apoptosis. To further
Bioactive phenolics from the fruits of Livistona chinensis.
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This study investigated the antioxidant and cytotoxic activity of the phenolics isolated from the fruits of Livistona chinensis. Four new compounds, 1-{ω-isoferul[6- (4-hydroxybutyl)pentadecanoic acid]}-glycerol (1), E-[6'-(5″-hydroxypentyl)tricosyl]-4-hydroxy-3-methoxycinnamate (2),
Cytotoxic ceramides and glycerides from the roots of Livistona chinensis.
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A 70% ethanol extract of the roots of Livistona chinensis has been investigated, led to the isolation of 13 compounds, including a new ceramide, (2S,3S,4R,9Z)-2-[(2R)-2-hydroxytricosanoylamino]-9-octadecene-1,3,4-triol (2), a new glycosyl ceramide,
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