lymphopenia/hypoxia

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[High-altitude hypoxia as a factor in the treatment of radiation and cytostatic lymphopenia in oncological patients].

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[Role of the hypophysis in the lymphopenia observed in acute anoxia].

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Activation-induced necroptosis contributes to B-cell lymphopenia in active systemic lupus erythematosus.

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B-cell abnormality including excessive activation and lymphopenia is a central feature of systemic lupus erythematosus (SLE). Although activation threshold, auto-reaction and death of B cells can be affected by intrinsical and/or external signaling, the underlying mechanisms are unclear. Herein, we

Acute hypoxia-reperfusion triggers immunocompromise in Nile tilapia.

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Inadequate dissolved oxygen in the aquatic environment is a well-established cause of fish morbidity and mortality. The specific effects of hypoxia on immune function in fish, however, are not well characterized. In this study, the effects of acute hypoxia followed by reoxygenation (rapid tissue

Leukocyte counts and neutrophil activity during 4 h of hypocapnic hypoxia equivalent to 4000 m.

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BACKGROUND Symptoms and signs of infectious disease are increased in subjects at altitude. Most infections at altitude are diagnosed clinically and do not have objective data to support the diagnosis. Since in vivo innate immune responses to hypoxia have not been thoroughly characterized, we

Differential expression of genes associated with T lymphocytes function in septic patients with hypoxemia challenge.

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This study aimed to assess gene expression alterations related to T lymphocytes function and explore their potential association with hypoxemia among septic patients.

Methods

This is a retrospective cohort clinical study with laboratory investigations.

Potential Immunotherapeutic Targets For Hypoxia Due to COVI-FLU

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The world is currently embroiled in a pandemic of coronavirus disease 2019 (COVID-19), a respiratory illness caused by the novel betacoronavirus SARS-CoV-2. The severity of COVID-19 disease ranges from asymptomatic to fatal acute respiratory distress syndrome (ARDS). In few patients, the disease

[Experimental research on the adaptogenic properties of Kryms'kyĭ balsam].

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The effect of balsam "Kryms'kyĭ" has been studied in chronic experiments on Wistar rats. It is proved that peroral administration of balsam "Kryms'kyĭ" to rat for 4-7 days enhances excretion of 17-KC, static and dynamic muscular workability, resistance to hypoxia, accelerates elimination of

Blood gas stability and hematological changes in experimentally-induced acute porcine pleuropneumonia.

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Blood gas and hematological responses to acute, mild Actinobacillus pleuropneumoniae infection of growing pigs was studied. Six pigs (average weight 10.1 kg) were experimentally infected intranasally with A. pleuropneumoniae serotype 5. Four pigs served as controls. Rectal temperatures and arterial

Cytokine response in pediatric patients with pandemic influenza H1N1 2009 virus infection and pneumonia: comparison with pediatric pneumonia without H1N1 2009 infection.

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OBJECTIVE We investigated serum cytokine levels in pediatric patients with pandemic influenza H1N1 2009 virus (H1N1) infection-pneumonia and in pediatric patients with pneumonia but without H1N1 infection, and examined correlations between cytokine levels and clinical/laboratory

[Pneumonia caused by non-opportunistic bacteria in patients infected with HIV. Incidence and evaluation of a non-invasive approach].

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BACKGROUND Pneumonia due to pathogenic bacteria is common in HIV infected patients. However, a global overview has not been yet performed and also the effectiveness of a non-invasive approach has not been tested. METHODS An open study was conducted in 1989 including all HIV infected patients with a

Comparative pulmonary effects of intraperitoneal inoculation of live v dead Escherichia coli.

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We studied the effect of 2.5 X 10(9) live Escherichia coli per kilogram v 2.7 X 10(9) dead E coli per kilogram injected into the peritoneal cavity of sheep with chronic pulmonary lymph fistulas. The effects of dead E coli were compared with those of live E coli, with respect to (1) pulmonary

Proposals for leflunomide use to avoid lung injury in patients with rheumatoid arthritis.

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Among the 5,043 consecutive patients registered in the postmarketing surveillance for leflunomide, 61 were reported to have lung injury and 24 died from it. The adjusted multivariate logistic regression analysis of the risk factors showed that preexisting interstitial lung disease posed the greatest

Influenza Virus in Community-Acquired Pneumonia: Current Understanding and Knowledge Gaps

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Influenza virus infection poses a heavy burden on global health and economics. With the advancement in viral pathogen detection methods, the role of virus infection in community-acquired pneumonia has been increasingly recognized. The disease spectrum of influenza ranges from asymptomatic infection

Pneumocystis carinii pneumonia in rheumatoid arthritis patients treated with methotrexate. A report of two cases.

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Use of methotrexate to treat rheumatoid arthritis is associated with pulmonary adverse effects in 3% to 5% of cases. In addition to immunoallergic lung disease, bronchitis and pneumonia due to pyogenic organisms, opportunistic lower respiratory tract infections have been reported, including, to our

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