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manganese/neoplasms

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Manganese superoxide dismutase Val16Ala polymorphism predicts resistance to chemotherapeutic drug cancer therapy

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STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not applicable BACKGROUND OF THE INVENTION Cancer is the second leading cause of death behind heart disease. In fact, cancer incidence and death figures account for about 10% of the U.S. population in certain

Manganese superoxide dismutase variants and uses thereof

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CROSS-REFERENCE TO RELATED APPLICATIONS This application is a 371 of PCT/EP2014/073597, filed Nov. 3, 2014, which claims the benefit of both Italian Patent Application No. RM2013A000608 filed Nov. 4, 2013 and European Patent Application 14178505.5 filed Jul. 25, 2014. FIELD OF THE INVENTION The

Method for protection against tumor metastasis formation

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention is generally directed to the fields of cancer biology and biochemistry. More particularly, the present invention is directed to a method for inhibiting the formation of metastases from primary tumors growing in mammals. 2.

Method for treating a cancer patient based on atomic therapeutic indexes and radiation

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FIELD OF THE INVENTION The present invention relates to the generation of an Atomic Therapeutic Indicator (ATI) for a test sample by the quantification of manganese; in voxels of a 3D region of the sample, wherein the 3D region is topographically defined by co-ordinates X'.times.Y'.times.Z. The ATI

Method for treating a cancer patient based on atomic therapeutic indexes and non-radiation therapy

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FIELD OF THE INVENTION The present invention relates to the generation of an Atomic Therapeutic Indicator (ATI) for a test sample by the quantification of manganese; in voxels of a 3D region of the sample, wherein the 3D region is topographically defined by co-ordinates X'.times.Y'.times.Z. The ATI

Methods to screen for ovarian cancer and myocardial infarction

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BACKGROUND OF THE INVENTION This invention relates to a monoclonal antibody having high specificity against human manganese-superoxide dismutase (hereinafter abbreviated as human Mn-SOD), a method for producing the monoclonal antibody, an assay reagent or assay kit and assay method by use thereof,

Method for analyzing blood for the presence of cancer cells

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CROSS-REFERENCE TO RELATED APPLICATIONS This is a 371 of PCT/EP2003/009229, filed 20 Aug. 2003 which claims priority from German Patent Application No. 102 38 046.5 filed 20 Aug. 2002. TECHNICAL FIELD The present invention relates to a method for investigating body fluids for cancer cells, the use

Methods of inhibiting manganese-containing superoxide dismutase 2 (MnSOD)

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TECHNICAL FIELD This invention relates to siRNA molecules, and more particularly to MnSOD siRNA molecules. BACKGROUND MnSOD plays an important role in protecting cells from injury due to oxidative stress, and is essential for aerobic life. MnSOD catalyzes the conversion of superoxide (O.sub.2.sup.-)

Compounds for use in the treatment of cancer

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FIELD OF INVENTION The present invention relates to a compound for use in the treatment of cancer. The invention also relates to the use of the compound in the manufacture of a medicament for the treatment of cancer. Also disclosed is a method of treatment of cancer in the human or non-human body

Calcium phosphate-based materials containing zinc, magnesium, fluoride and carbonate

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FIELD OF THE INVENTION This invention relates generally to compositions and methods useful in the prevention and treatment of osteoporosis and for bone and fracture repair. More specifically, the invention relates to slow-releasing calcium phosphate-based materials incorporating Mg, Zn, F, carbonate

Composition for improving membrane composition and functioning of cells

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FIELD The invention relates to nutraceutical and pharmaceutical compositions, more in particular compositions that can improve membrane composition and functioning of cells and through this the general cell functioning. BACKGROUND Membranes in living cells are known to have many important functions.

Composition for improving membrane composition and functioning cells

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FIELD The invention relates to nutraceutical and pharmaceutical compositions, more in particular compositions that can improve membrane composition and functioning of cells and through this the general cell functioning. BACKGROUND Membranes in living cells are known to have many important functions.

Composition for improving membrane composition and functioning of cells

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FIELD The invention relates to nutraceutical and pharmaceutical compositions, more in particular compositions that can improve membrane composition and functioning of cells and through this the general cell functioning. BACKGROUND Membranes in living cells are known to have many important functions.

Composition for improving membrane composition and functioning of cells

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FIELD The invention relates to nutraceutical and pharmaceutical compositions, more in particular compositions that can improve membrane composition and functioning of cells and through this the general cell functioning. BACKGROUND Membranes in living cells are known to have many important functions.

Composition for improving membrane composition and functioning of cells

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FIELD The invention relates to nutraceutical and pharmaceutical compositions, more in particular compositions that can improve membrane composition and functioning of cells and through this the general cell functioning. BACKGROUND Membranes in living cells are known to have many important functions.
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