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2 results
Marrubiin, a constituent of Leonotis leonurus, alleviates diabetic symptoms.
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OBJECTIVE
Marrubiin and an organic extract of Leonotis leonurus were tested in vitro and in vivo for their antidiabetic and anti-inflammatory activities.
METHODS
INS-1 cells were cultured under normo- and hyperglycemic conditions conditions. An in vivo animal model confirmed the biological
The cardioprotective effects of marrubiin, a diterpenoid found in Leonotis leonurus extracts.
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BACKGROUND
Leonotis leonurus L. (Lamiaceae) is used as a traditional medicine for a variety of ailments in South Africa. The diterpene marrubiin is the major product constituent in specimens of this plant occurring in South Africa.
METHODS
Marrubiin isolated from South African specimens of L.
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