multiple endocrine neoplasia type 2b/rhapis

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Mucocutaneous neuromas: an underrecognized manifestation of PTEN hamartoma-tumor syndrome.

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BACKGROUND The spectrum of clinical findings associated with PTEN tumor suppressor gene germline mutations, referred to as PTEN hamartoma-tumor syndrome (PHTS), includes Cowden and Bannayan-Riley-Ruvalcaba syndromes. Although the skin is the ectodermal structure most often affected by these

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