murraya alata/necrosis

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Evaluation of anti-inflammatory and antinociceptive activities of Murraya exotica.

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BACKGROUND Leaves of Murraya exotica L. (Rutaceae) are used for the treatment of various disorders such as cough, fever, and infectious wounds, as well as alleviating pains in folk medicine in southern China. OBJECTIVE The objectives of this study were to investigate the in vivo antinociceptive and

Isosibiricin inhibits microglial activation by targeting the dopamine D1/D2 receptor-dependent NLRP3/caspase-1 inflammasome pathway.

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Microglia-mediated neuroinflammation is a crucial risk factor for neurological disorders. Recently, dopamine receptors have been found to be involved in multiple immunopathological processes and considered as valuable therapeutic targets for inflammation-associated neurologic diseases. In this study

Immunomodulatory effect of leaf extract of Murraya koenigii in diabetic mice.

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BACKGROUND Extracts of different parts of Murraya koenigii were traditionally used as medicine in many countries for the treatment of various diseases including diabetes. OBJECTIVE To delineate whether aqueous (AEM) and 50% methanol (MEM) leaf extracts have immunomodulatory properties to regulate

Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii.

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Therapy that directly targets apoptosis and/or inflammation could be highly effective for the treatment of cancer. Murraya koenigii is an edible herb that has been traditionally used for cancer treatment as well as inflammation. Here, we describe that girinimbine, a carbazole alkaloid isolated from

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