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muscular dystrophies/cannabis

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Muscular dystrophy in mice after chronic subcutaneous treatment with cannabinoids.

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Swiss male albino mice were treated subcutaneously with the main cannabinoids (CBN, CBD, delta9-THC) at the dosage of 1 mg/kg per day for 30 days, and with the crude resin. At the end of the treatment, after supramaximal stimulation of the sciatic nerve, a significant decrease of both maximal twitch

Effects of non-euphoric plant cannabinoids on muscle quality and performance of dystrophic mdx mice.

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OBJECTIVE Duchenne muscular dystrophy (DMD), caused by dystrophin deficiency, results in chronic inflammation and irreversible skeletal muscle degeneration. Moreover, the associated impairment of autophagy greatly contributes to the aggravation of muscle damage. We explored the possibility of using
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