myricetin/fatigue

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Protective effects of myricetin on acute hypoxia-induced exercise intolerance and mitochondrial impairments in rats.

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OBJECTIVE Exercise tolerance is impaired in hypoxia. The aim of this study was to evaluate the effects of myricetin, a dietary flavonoid compound widely found in fruits and vegetables, on acute hypoxia-induced exercise intolerance in vivo and in vitro. METHODS Male rats were administered myricetin

Myricetin improves endurance capacity by inducing muscle fiber type conversion via miR-499.

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Reprogramming of fast-to-slow myofiber switch can improve endurance capacity and alleviate fatigue. Accumulating evidence suggests that a muscle-specific microRNA, miR-499 plays a crucial role in myofiber type transition. In this study, we assessed the effects of natural flavonoid

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