neutropenia/nicotine

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Efficient transient expression of human GM-CSF protein in Nicotiana benthamiana using potato virus X vector.

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The human granulocyte macrophage colony-stimulating factor (GM-CSF) is a glycoprotein with important clinical applications for the treatment of neutropenia and aplastic anemia and reducing infections associated with bone marrow transplants. We evaluated the potential for using a potato virus X (PVX)

Enhanced heterologous expression of biologically active human granulocyte colony stimulating factor in transgenic tobacco BY-2 cells by localization to endoplasmic reticulum.

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Tobacco Bright Yellow-2 (BY-2) cells, one of the best characterized cell lines is an attractive expression system for heterologous protein expression. However, the expression of foreign proteins is currently hampered by their low yield, which is partially the result of proteolytic degradation. Human

[Development and implementation of clozapine protocol in patients with schizophrenia in Greece]

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Clozapine is an atypical antipsychotic used for the treatment of resistant schizophrenia, exhibiting significant advantages over other antipsychotic agents. Clozapine efficacy is well established in people diagnosed with schizophrenia via reducing both positive and negative symptoms. Also, is

The potentiating actions of cigarette smoking on ethanol-induced gastric mucosal damage in rats.

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OBJECTIVE Cigarette smoking has been associated with peptic ulceration. However, the ulcerogenic mechanisms are still undefined. The aim of this study was to investigate the effects and possible mechanisms of cigarette smoke on ethanol- or cold-restraint stress-induced gastric damage. METHODS Rats

Hematological profile and risk factors associated with pulmonary tuberculosis patients in Quetta, Pakistan.

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OBJECTIVE Tuberculosis (TB) is a chronic debilitating infectious disease affecting more than one third of the global population. This study was designed to investigate different peripheral blood parameters and risk factors in TB patients. METHODS A total of 600 (Male, 238 and Female, 362) aging

Recurrent respiratory infections: why not talking about it any more?

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Recurrent respiratory infections (RRIs) are a common and benign condition affecting about 6% of schoolchildren. Only mild, likely postinfective, modifications of the immune system have been proven, and parents should be reassured that the condition is self-limited. Nevertheless, if not correctly

Yield and costs of screening growth-retarded infants for torch infections.

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Many infants with intrauterine growth retardation (IUGR) are screened for TORCH infections. The yield and costs of such a practice may not be justifiable. Medical charts of infants with IUGR who had a workup for toxoplasmosis, other (infections), rubella, cytomegalovirus (infection), and herpes

Prophylaxis of invasive aspergillosis with voriconazole or caspofungin during building work in patients with acute leukemia.

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BACKGROUND Invasive aspergillosis is a common life-threatening infection in patients with acute leukemia. The presence of building work near to hospital wards in which these patients are cared for is an important risk factor for the development of invasive aspergillosis. This study assessed the

Behavioral and psychological predictors of chemotherapy adherence in patients with advanced non-small cell lung cancer.

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OBJECTIVE Dose delays and reductions in chemotherapy due to hematologic toxicities are common among patients with advanced non-small cell lung cancer (NSCLC). However, limited data on behavioral or psychological predictors of chemotherapy adherence exist. The goal of this study was to explore the

Mild serotonin syndrome associated with concurrent linezolid and fluoxetine.

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OBJECTIVE A case of serotonin syndrome that developed during concurrent linezolid and fluoxetine is presented. CONCLUSIONS A 23-year-old white male patient was originally admitted to receive intravenous chemotherapy for acute myelogenous leukemia. He had a history of intravenous amphetamine abuse,

Leukocytes and the risk of ischemic diseases.

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Predictive indexes for atherosclerotic risk are imperfect, suggesting that there are predictive factors not commonly considered. Such a factor may be the white blood cell (WBC) count. Epidemiologic studies have shown correlations between the WBC count and the risk of myocardial infarction and

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