nut hypersensitivity/juglans regia

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Walnut oral immunotherapy for desensitisation of walnut and additional tree nut allergies (Nut CRACKER): a single-centre, prospective cohort study.

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The safety and efficacy of oral immunotherapy for tree nut allergy has not been demonstrated to date, and its effectiveness is complicated by the high prevalence of co-allergies to several nuts. This study aimed to investigate the use of walnut oral immunotherapy in the desensitisation

Clinical and Molecular Characterization of Walnut and Pecan Allergy (NUT CRACKER Study).

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Diagnostic methods for distinguishing walnut-allergic patients from walnut-sensitized but walnut-tolerant individuals are limited. Furthermore, characteristics of single walnut versus dual walnut-pecan allergy are lacking.To provide clinical and molecular

Is There Any Necessity to Prescribe Consumption of Walnuts Cooked by Different Processing Techniques to Patients With Walnut Allergy?

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The present study focused on identifying the usual methods of cooking walnuts in order to investigate changes in walnut allergen activity caused by cooking and evaluated the allergenic changes in walnut proteins within raw, dry-fried and boiled walnuts. Previous studies have reported a decrease in

Self-reported prevalence of clinical features of allergy to nuts and seeds, and seafood in university students.

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UNASSIGNED In developing countries, there is a lack of epidemiological information related to food hypersensitivity, including nuts and seafood. UNASSIGNED The aim was to determine the prevalence of allergic reactions and clinical manifestations associated with the consumption of nuts and seeds or

Linear IgE epitope mapping of the English walnut (Juglans regia) major food allergen, Jug r 1.

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BACKGROUND Peanut and tree nut allergies can be life-threatening, and they appear to be growing in prevalence. Jug r 1, a 2S albumin seed storage protein, was previously characterized as a major English walnut food allergen. OBJECTIVE We sought to identify the linear IgE-binding epitopes of Jug r 1

A Prospective Validation of the NUT CRACKER Diagnostic Algorithm for Walnut and Pecan Allergy with Prediction of Severity

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Background: We previously devised an algorithm utilizing skin prick tests (SPT), basophil activation tests (BAT) and co-allergy status to reduce the need for oral food challenges (OFC) in 63 patients with suspected walnut/pecan

Anaphylaxis due to Brazil nut skin testing in a walnut-allergic subject.

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The diagnosis and management of nut allergy can be difficult because of the possible severity of the clinical manifestations and the cross reactivity between different species. We report a case of anaphylaxis due to skin testing in a young adult with clinically ascertained walnut allergy. After an

Component resolved diagnosis of walnut allergy in young children: Jug r 1 as a major walnut allergen.

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Walnuts (WN) are one of the main causes of tree nut allergies. However, the potential value of component resolved diagnosis (CRD) for WN allergy is controversial.We analyzed the clinical and immunological features of clinical WN allergy and the usefulness

Particularities in a Child With Cashew Nut Allergy.

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Food allergy affects many young children and tree nut allergy is accountable for a large number of severe, life-threatening anaphylactic reactions. Cross-reactivity can occur not only with foods that are in the same biological family but also between certain fruits or vegetables and latex

Systemic allergic reaction to coconut (Cocos nucifera) in 2 subjects with hypersensitivity to tree nut and demonstration of cross-reactivity to legumin-like seed storage proteins: new coconut and walnut food allergens.

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BACKGROUND Two patients with tree nut allergy manifested by life-threatening systemic reactions reported the subsequent onset of systemic reactions after the consumption of coconut. OBJECTIVE Herein, the IgE-binding proteins from coconut are described, and in vitro cross-reactivity with other nuts

Detection of allergy to nuts by the radioallergosorbent test.

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The diagnosis of food allergy is often difficult to make by conventional means. Histories are frequently ambiguous, and skin testing is of dubious reliability because of the number of false-positive and false-negative reactions. We have evaluated the radioallergosorbent test (RAST) for the in vitro

Effects of thermal treatment on walnut detection and allergenicity.

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BACKGROUND Peanuts and tree nut allergies pose an increasing food safety problem. The aim of our study was to test the accuracy of different commercial enzyme-linked immunosorbent assay (ELISA) kits in the detection of the presence of walnuts in untreated and heat exposed food samples. The effects

Tree nut allergies: Allergen homology, cross-reactivity, and implications for therapy.

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Tree nut allergy is a potentially life-threatening disease that is increasing in prevalence, now affecting 1% of the general population in the United States. While other food allergies often resolve spontaneously, tree nut allergies are outgrown in less than 10% of cases. Due to the likelihood of

Is Microarray Analysis Really Useful and Sufficient to Diagnose Nut Allergy in the Mediterranean Area?

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BACKGROUND Component-based diagnosis on multiplex platforms is widely used in food allergy but its clinical performance has not been evaluated in nut allergy. OBJECTIVE To assess the diagnostic performance of a commercial protein microarray in the determination of specific IgE (sIgE) in peanut,

Interpretation of tests for nut allergy in one thousand patients, in relation to allergy or tolerance.

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BACKGROUND Peanut and tree nut allergy are common, increasing in prevalence and the commonest food cause of anaphylaxis. In the USA, 7.8% are sensitized (have nut-specific IgE), but not all those sensitized are allergic. Lack of data makes interpretation of tests for nut-specific IgE

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