Study subjects:
Study subjects (n=5) will be recruited from the pool of patients attending Kuwait University Dental Clinic. Informed written consent will be obtained from all subjects. An approval for using human subjects in the study will be obtained from the Ethics Committee of HSC, Kuwait
The study design was a split-mouth placebo-controlled randomized clinical trial according to CONSORT recommendations. Patients were recruited in the Clinic of Dental School of University of Chile according to inclusion criteria.All patients signed the informed consent approved by the Ethics
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